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| 12.04.2019 | 20:00 | SC Cambuur | - | Jong FC Utrecht | 4:1 (2:1) | |
| 20:00 | FC Volendam | - | Jong PSV | 0:3 (0:1) | ||
| 20:00 | FC Dordrecht | - | MVV Maastricht | 1:1 (1:0) | ||
| 20:00 | FC Eindhoven | - | Roda JC Kerkrade | 1:2 (1:1) | ||
| 20:00 | NEC Nijmegen | - | Helmond Sport | 3:2 (1:1) | ||
| 20:00 | Almere City FC | - | FC Den Bosch | 3:1 (2:0) | ||
| 20:00 | FC Twente | - | Telstar | 1:0 (1:0) | ||
| 20:00 | Jong AZ Alkmaar | - | RKC Waalwijk | 2:4 (0:3) | ||
| 14.04.2019 | 14:30 | Sparta Rotterdam | - | TOP Oss | 1:4 (1:1) | |
| 15.04.2019 | 20:00 | Jong Ajax | - | Go Ahead Eagles | 5:2 (2:1) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Twente | 34 | 24 | 3 | 7 | 65:31 | 34 | 75 |
| 2 |
|
Sparta Rotterdam | 34 | 18 | 11 | 5 | 71:39 | 32 | 65 |
| 3 |
|
Go Ahead Eagles | 34 | 18 | 6 | 10 | 60:49 | 11 | 60 |
| 4 |
|
Jong PSV | 34 | 16 | 9 | 9 | 71:55 | 16 | 57 |
| 5 |
|
FC Den Bosch | 34 | 16 | 8 | 10 | 58:45 | 13 | 56 |
| 6 |
|
Almere City FC | 34 | 17 | 5 | 12 | 54:51 | 3 | 56 |
| 7 |
|
Jong Ajax | 34 | 15 | 7 | 12 | 69:59 | 10 | 52 |
| 8 |
|
RKC Waalwijk | 34 | 16 | 4 | 14 | 57:49 | 8 | 52 |
| 9 |
|
TOP Oss | 34 | 15 | 7 | 12 | 41:39 | 2 | 52 |
| 10 |
|
Roda JC Kerkrade | 34 | 14 | 9 | 11 | 55:51 | 4 | 51 |
| 11 |
|
SC Cambuur | 34 | 14 | 8 | 12 | 51:43 | 8 | 50 |
| 12 |
|
NEC Nijmegen | 34 | 13 | 9 | 12 | 63:56 | 7 | 48 |
| 13 |
|
FC Eindhoven | 34 | 13 | 8 | 13 | 48:40 | 8 | 47 |
| 14 |
|
MVV Maastricht | 34 | 12 | 11 | 11 | 43:46 | -3 | 47 |
| 15 |
|
Telstar | 34 | 13 | 5 | 16 | 40:53 | -13 | 44 |
| 16 |
|
FC Volendam | 34 | 9 | 12 | 13 | 41:54 | -13 | 39 |
| 17 |
|
FC Dordrecht | 34 | 8 | 8 | 18 | 46:75 | -29 | 32 |
| 18 |
|
Jong AZ Alkmaar | 34 | 5 | 11 | 18 | 40:62 | -22 | 26 |
| 19 |
|
Helmond Sport | 34 | 3 | 9 | 22 | 33:63 | -30 | 18 |
| 20 |
|
Jong FC Utrecht | 34 | 3 | 6 | 25 | 39:85 | -46 | 15 |
| Promotie | |
| Play-offs | |
| Play-offs |
