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| 19.04.2019 | 20:00 | Sparta Rotterdam | - | Helmond Sport | 3:1 (2:0) | |
| 20:00 | FC Volendam | - | NEC Nijmegen | 2:3 (0:2) | ||
| 20:00 | RKC Waalwijk | - | FC Dordrecht | 4:4 (0:1) | ||
| 20:00 | FC Eindhoven | - | SC Cambuur | 2:2 (0:0) | ||
| 20:00 | Go Ahead Eagles | - | Jong PSV | 2:1 (2:1) | ||
| 20:00 | FC Den Bosch | - | Jong FC Utrecht | 2:2 (1:1) | ||
| 20:00 | Roda JC Kerkrade | - | TOP Oss | 1:1 (0:0) | ||
| 20:00 | Almere City FC | - | Telstar | 2:0 (1:0) | ||
| 20:00 | Jong AZ Alkmaar | - | MVV Maastricht | 2:3 (0:1) | ||
| 29.04.2019 | 20:00 | Jong Ajax | - | FC Twente | 2:5 (2:2) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Twente | 35 | 25 | 3 | 7 | 70:33 | 37 | 78 |
| 2 |
|
Sparta Rotterdam | 35 | 19 | 11 | 5 | 74:40 | 34 | 68 |
| 3 |
|
Go Ahead Eagles | 35 | 19 | 6 | 10 | 62:50 | 12 | 63 |
| 4 |
|
Almere City FC | 35 | 18 | 5 | 12 | 56:51 | 5 | 59 |
| 5 |
|
Jong PSV | 35 | 16 | 9 | 10 | 72:57 | 15 | 57 |
| 6 |
|
FC Den Bosch | 35 | 16 | 9 | 10 | 60:47 | 13 | 57 |
| 7 |
|
RKC Waalwijk | 35 | 16 | 5 | 14 | 61:53 | 8 | 53 |
| 8 |
|
TOP Oss | 35 | 15 | 8 | 12 | 42:40 | 2 | 53 |
| 9 |
|
Jong Ajax | 35 | 15 | 7 | 13 | 71:64 | 7 | 52 |
| 10 |
|
Roda JC Kerkrade | 35 | 14 | 10 | 11 | 56:52 | 4 | 52 |
| 11 |
|
NEC Nijmegen | 35 | 14 | 9 | 12 | 66:58 | 8 | 51 |
| 12 |
|
SC Cambuur | 35 | 14 | 9 | 12 | 53:45 | 8 | 51 |
| 13 |
|
MVV Maastricht | 35 | 13 | 11 | 11 | 46:48 | -2 | 50 |
| 14 |
|
FC Eindhoven | 35 | 13 | 9 | 13 | 50:42 | 8 | 48 |
| 15 |
|
Telstar | 35 | 13 | 5 | 17 | 40:55 | -15 | 44 |
| 16 |
|
FC Volendam | 35 | 9 | 12 | 14 | 43:57 | -14 | 39 |
| 17 |
|
FC Dordrecht | 35 | 8 | 9 | 18 | 50:79 | -29 | 33 |
| 18 |
|
Jong AZ Alkmaar | 35 | 5 | 11 | 19 | 42:65 | -23 | 26 |
| 19 |
|
Helmond Sport | 35 | 3 | 9 | 23 | 34:66 | -32 | 18 |
| 20 |
|
Jong FC Utrecht | 35 | 3 | 7 | 25 | 41:87 | -46 | 16 |
| Promotie | |
| Play-offs | |
| Play-offs |
