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| 28.10.2022 | 20:00 | Almere City FC | - | Heracles Almelo | 3:2 (0:2) | |
| 20:00 | FC Den Bosch | - | NAC Breda | 3:2 (1:0) | ||
| 20:00 | FC Eindhoven | - | Jong PSV | 2:2 (1:0) | ||
| 20:00 | De Graafschap | - | TOP Oss | 2:0 (1:0) | ||
| 20:00 | Helmond Sport | - | ADO Den Haag | 2:1 (1:0) | ||
| 20:00 | PEC Zwolle | - | MVV Maastricht | 0:1 (0:1) | ||
| 20:00 | Roda JC Kerkrade | - | Jong FC Utrecht | 4:1 (1:1) | ||
| 20:00 | Telstar | - | FC Dordrecht | 2:2 (2:2) | ||
| 20:00 | VVV-Venlo | - | Jong AZ Alkmaar | 1:2 (1:1) | ||
| 31.10.2022 | 20:00 | Jong Ajax | - | Willem II | 1:2 (1:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Heracles Almelo | 13 | 9 | 1 | 3 | 34:18 | 16 | 28 |
| 2 |
|
MVV Maastricht | 13 | 8 | 3 | 2 | 25:19 | 6 | 27 |
| 3 |
|
PEC Zwolle | 13 | 8 | 2 | 3 | 28:17 | 11 | 26 |
| 4 |
|
FC Eindhoven | 13 | 6 | 5 | 2 | 22:15 | 7 | 23 |
| 5 |
|
Willem II | 13 | 6 | 4 | 3 | 20:15 | 5 | 22 |
| 6 |
|
Roda JC Kerkrade | 13 | 6 | 3 | 4 | 25:19 | 6 | 21 |
| 7 |
|
Jong AZ Alkmaar | 13 | 6 | 2 | 5 | 22:18 | 4 | 20 |
| 8 |
|
Almere City FC | 13 | 6 | 2 | 5 | 20:19 | 1 | 20 |
| 9 |
|
VVV-Venlo | 13 | 5 | 3 | 5 | 19:23 | -4 | 18 |
| 10 |
|
Jong PSV | 13 | 4 | 5 | 4 | 21:20 | 1 | 17 |
| 11 |
|
NAC Breda | 13 | 5 | 2 | 6 | 19:21 | -2 | 17 |
| 12 |
|
Telstar | 13 | 4 | 5 | 4 | 14:19 | -5 | 17 |
| 13 |
|
Jong Ajax | 13 | 4 | 4 | 5 | 21:20 | 1 | 16 |
| 14 |
|
De Graafschap | 13 | 4 | 3 | 6 | 19:21 | -2 | 15 |
| 15 |
|
FC Den Bosch | 13 | 5 | 0 | 8 | 20:24 | -4 | 15 |
| 16 |
|
FC Dordrecht | 13 | 4 | 3 | 6 | 15:19 | -4 | 15 |
| 17 |
|
ADO Den Haag | 13 | 4 | 3 | 6 | 17:22 | -5 | 15 |
| 18 |
|
TOP Oss | 13 | 4 | 1 | 8 | 16:20 | -4 | 13 |
| 19 |
|
Helmond Sport | 13 | 4 | 0 | 9 | 12:24 | -12 | 12 |
| 20 |
|
Jong FC Utrecht | 13 | 1 | 3 | 9 | 9:25 | -16 | 6 |
| Promotie | |
| Play-offs |
