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| 30.01.2009 | 20:00 | VVV-Venlo | - | FC Eindhoven | 6:0 (2:0) | |
| 20:00 | Helmond Sport | - | MVV Maastricht | 2:1 (1:1) | ||
| 20:00 | Fortuna Sittard | - | SBV Excelsior | 1:1 (1:0) | ||
| 20:00 | TOP Oss | - | Telstar | 3:0 (1:0) | ||
| 20:00 | FC Dordrecht | - | FC Emmen | 1:0 (1:0) | ||
| 20:00 | Go Ahead Eagles | - | RKC Waalwijk | 0:0 (0:0) | ||
| 20:00 | AGOVV | - | FC Den Bosch | 3:2 (1:1) | ||
| 03.02.2009 | 20:00 | HFC Haarlem | - | RBC Roosendaal | 2:0 (1:0) | |
| 17.02.2009 | 20:00 | SC Cambuur | - | FC Zwolle | 1:2 (1:1) | |
| 24.02.2009 | 20:00 | BV Veendam | - | FC Omniworld | 0:2 (0:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
VVV-Venlo | 24 | 17 | 3 | 4 | 60:24 | 36 | 54 |
| 2 |
|
RKC Waalwijk | 24 | 10 | 13 | 1 | 40:21 | 19 | 43 |
| 3 |
|
SC Cambuur | 24 | 12 | 5 | 7 | 44:35 | 9 | 41 |
| 4 |
|
FC Zwolle | 24 | 11 | 7 | 6 | 41:35 | 6 | 40 |
| 5 |
|
SBV Excelsior | 24 | 10 | 9 | 5 | 35:23 | 12 | 39 |
| 6 |
|
HFC Haarlem | 24 | 11 | 3 | 10 | 31:35 | -4 | 36 |
| 7 |
|
FC Den Bosch | 24 | 9 | 8 | 7 | 42:32 | 10 | 35 |
| 8 |
|
MVV Maastricht | 24 | 9 | 8 | 7 | 37:28 | 9 | 35 |
| 9 |
|
Helmond Sport | 24 | 9 | 8 | 7 | 36:33 | 3 | 35 |
| 10 |
|
Go Ahead Eagles | 24 | 8 | 9 | 7 | 22:27 | -5 | 33 |
| 11 |
|
AGOVV | 24 | 9 | 4 | 11 | 38:45 | -7 | 31 |
| 12 |
|
Telstar | 24 | 7 | 8 | 9 | 34:38 | -4 | 29 |
| 13 |
|
Fortuna Sittard | 24 | 7 | 7 | 10 | 28:39 | -11 | 28 |
| 14 |
|
BV Veendam | 24 | 7 | 8 | 9 | 30:38 | -8 | 26 |
| 15 |
|
TOP Oss | 24 | 7 | 5 | 12 | 28:41 | -13 | 26 |
| 16 |
|
RBC Roosendaal | 24 | 6 | 7 | 11 | 27:32 | -5 | 25 |
| 17 |
|
FC Eindhoven | 24 | 6 | 10 | 8 | 41:50 | -9 | 25 |
| 18 |
|
FC Dordrecht | 24 | 5 | 7 | 12 | 24:28 | -4 | 22 |
| 19 |
|
FC Emmen | 24 | 5 | 6 | 13 | 28:48 | -20 | 21 |
| 20 |
|
FC Omniworld | 24 | 5 | 5 | 14 | 26:40 | -14 | 20 |
| Promotie | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs |
