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| 09.12.2011 | 20:00 | SC Cambuur | - | SC Veendam | 5:1 (3:1) | |
| 20:00 | FC Eindhoven | - | FC Den Bosch | 2:2 (1:1) | ||
| 20:00 | TOP Oss | - | Telstar | 3:1 (1:0) | ||
| 20:00 | AGOVV | - | FC Dordrecht | 2:3 (1:1) | ||
| 20:00 | FC Emmen | - | FC Zwolle | 1:2 (1:1) | ||
| 20:00 | FC Volendam | - | Helmond Sport | 3:1 (2:1) | ||
| 20:00 | Fortuna Sittard | - | Willem II | 3:1 (0:0) | ||
| 20:00 | Sparta Rotterdam | - | MVV Maastricht | 0:0 (0:0) | ||
| 20:00 | Go Ahead Eagles | - | Almere City FC | 2:2 (1:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Zwolle | 16 | 13 | 2 | 1 | 42:14 | 28 | 41 |
| 2 |
|
FC Eindhoven | 16 | 9 | 4 | 3 | 25:14 | 11 | 31 |
| 3 |
|
SC Cambuur | 16 | 9 | 2 | 5 | 40:26 | 14 | 29 |
| 4 |
|
Willem II | 16 | 9 | 1 | 6 | 31:22 | 9 | 28 |
| 5 |
|
FC Volendam | 16 | 8 | 3 | 5 | 32:22 | 10 | 27 |
| 6 |
|
Sparta Rotterdam | 16 | 7 | 5 | 4 | 28:17 | 11 | 26 |
| 7 |
|
FC Den Bosch | 16 | 6 | 6 | 4 | 28:16 | 12 | 24 |
| 8 |
|
Almere City FC | 16 | 7 | 3 | 6 | 31:28 | 3 | 24 |
| 9 |
|
FC Dordrecht | 16 | 6 | 6 | 4 | 25:34 | -9 | 24 |
| 10 |
|
Go Ahead Eagles | 16 | 6 | 4 | 6 | 29:29 | 0 | 22 |
| 11 |
|
MVV Maastricht | 16 | 6 | 4 | 6 | 28:31 | -3 | 22 |
| 12 |
|
Helmond Sport | 16 | 6 | 3 | 7 | 28:34 | -6 | 21 |
| 13 |
|
Fortuna Sittard | 16 | 5 | 4 | 7 | 29:28 | 1 | 19 |
| 14 |
|
TOP Oss | 16 | 5 | 3 | 8 | 32:36 | -4 | 18 |
| 15 |
|
Telstar | 16 | 4 | 2 | 10 | 27:40 | -13 | 14 |
| 16 |
|
SC Veendam | 16 | 2 | 5 | 9 | 27:35 | -8 | 11 |
| 17 |
|
FC Emmen | 16 | 4 | 3 | 9 | 16:35 | -19 | 9 |
| 18 |
|
AGOVV | 16 | 1 | 2 | 13 | 14:51 | -37 | 5 |
| Promotie | |
| Play-offs | |
| Degradatie |
