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| 08.10.2022 | 03:00 | Alianza | - | Deportivo del Este | 1:0 (1:0) | |
| 23:00 | Árabe Unido | - | Sporting San Miguelito | 1:1 (1:1) | ||
| 09.10.2022 | 01:15 | Atlético Chiriquí | - | San Francisco FC | 0:4 (0:0) | |
| 03:30 | Tauro FC | - | Plaza Amador | 0:0 (0:0) | ||
| 23:00 | Independiente de La Chorrera | - | Herrera FC | 2:3 (2:1) | ||
| 10.10.2022 | 01:15 | UD Universitario | - | Veraguas United | 3:1 (2:1) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| 1 | |||||||||
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Plaza Amador | 14 | 6 | 5 | 3 | 17:13 | 4 | 23 |
| 2 |
|
Alianza | 14 | 7 | 2 | 5 | 14:11 | 3 | 23 |
| 3 |
|
Sporting San Miguelito | 14 | 5 | 7 | 2 | 18:12 | 6 | 22 |
| 4 |
|
Árabe Unido | 14 | 6 | 4 | 4 | 17:12 | 5 | 22 |
| 5 |
|
Deportivo del Este | 14 | 5 | 4 | 5 | 20:18 | 2 | 19 |
| 6 |
|
Tauro FC | 14 | 5 | 3 | 6 | 12:15 | -3 | 18 |
| 2 | |||||||||
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Independiente de La Chorrera | 14 | 8 | 2 | 4 | 22:11 | 11 | 26 |
| 2 |
|
UD Universitario | 14 | 6 | 5 | 3 | 23:18 | 5 | 23 |
| 3 |
|
San Francisco FC | 14 | 4 | 2 | 8 | 17:17 | 0 | 14 |
| 4 |
|
Herrera FC | 14 | 2 | 7 | 5 | 10:24 | -14 | 13 |
| 5 |
|
Veraguas United | 14 | 2 | 5 | 7 | 12:18 | -6 | 11 |
| 6 |
|
Atlético Chiriquí | 14 | 1 | 8 | 5 | 6:19 | -13 | 11 |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs |
