 |
 |
|
|
| 26.08.2022 | 23:00 | Guaireña FC | - | Club Nacional | 1:3 (0:1) | |
| 27.08.2022 | 01:15 | General Caballero DJLM | - | Cerro Porteño | 1:1 (0:1) | |
| 22:00 | Libertad | - | Guaraní | 2:2 (1:1) | ||
| 28.08.2022 | 00:30 | Club Olimpia | - | Resistencia SC | 1:1 (1:0) | |
| 21:30 | Sportivo Ameliano | - | 12 de Octubre de Itauguá | 2:0 (2:0) | ||
| 29.08.2022 | 00:00 | Tacuary | - | Sol de América | 1:0 (0:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Libertad | 8 | 5 | 1 | 2 | 21:11 | 10 | 16 |
| 2 |
|
Club Olimpia | 8 | 5 | 1 | 2 | 14:8 | 6 | 16 |
| 3 |
|
Club Nacional | 8 | 4 | 3 | 1 | 12:7 | 5 | 15 |
| 4 |
|
Cerro Porteño | 8 | 4 | 3 | 1 | 9:5 | 4 | 15 |
| 5 |
|
Tacuary | 8 | 4 | 2 | 2 | 10:5 | 5 | 14 |
| 6 |
|
Sportivo Ameliano | 8 | 4 | 0 | 4 | 10:9 | 1 | 12 |
| 7 |
|
Guaireña FC | 8 | 3 | 1 | 4 | 10:12 | -2 | 10 |
| 8 |
|
Resistencia SC | 8 | 2 | 4 | 2 | 8:11 | -3 | 10 |
| 9 |
|
Sol de América | 8 | 3 | 0 | 5 | 6:12 | -6 | 9 |
| 10 |
|
Guaraní | 8 | 1 | 4 | 3 | 6:9 | -3 | 7 |
| 11 |
|
General Caballero DJLM | 8 | 2 | 1 | 5 | 8:16 | -8 | 7 |
| 12 |
|
12 de Octubre de Itauguá | 8 | 1 | 0 | 7 | 5:14 | -9 | 3 |
| Copa Libertadores |
