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| 29.04.2006 | 20:00 | CD Nacional | - | Boavista | 1:0 (0:0) | |
| 30.04.2006 | 19:30 | SL Benfica | - | Vitória Setúbal | 1:0 (1:0) | |
| 19:30 | CS Marítimo | - | Paços de Ferreira | 1:1 (1:1) | ||
| 19:30 | Os Belenenses | - | Académica de Coimbra | 0:0 (0:0) | ||
| 19:30 | Sporting Braga | - | Gil Vicente | 1:1 (0:0) | ||
| 19:30 | Rio Ave FC | - | Sporting CP | 1:3 (1:2) | ||
| 19:30 | Naval 1° de Maio | - | União Leiria | 0:2 (0:2) | ||
| 19:30 | Estrela Amadora | - | FC Penafiel | 1:0 (0:0) | ||
| 19:30 | FC Porto | - | Vitória Guimarães | 3:1 (0:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Porto | 33 | 24 | 6 | 3 | 53:15 | 38 | 78 |
| 2 |
|
Sporting CP | 33 | 21 | 6 | 6 | 49:24 | 25 | 69 |
| 3 |
|
SL Benfica | 33 | 20 | 7 | 6 | 50:26 | 24 | 67 |
| 4 |
|
Sporting Braga | 33 | 17 | 7 | 9 | 38:21 | 17 | 58 |
| 5 |
|
CD Nacional | 33 | 14 | 9 | 10 | 39:31 | 8 | 51 |
| 6 |
|
Boavista | 33 | 12 | 13 | 8 | 36:28 | 8 | 49 |
| 7 |
|
Vitória Setúbal | 33 | 14 | 3 | 16 | 27:32 | -5 | 45 |
| 8 |
|
União Leiria | 33 | 12 | 8 | 13 | 39:40 | -1 | 44 |
| 9 |
|
CS Marítimo | 33 | 10 | 13 | 10 | 36:35 | 1 | 43 |
| 10 |
|
Estrela Amadora | 33 | 11 | 9 | 13 | 30:33 | -3 | 42 |
| 11 |
|
Paços de Ferreira | 33 | 10 | 9 | 14 | 35:48 | -13 | 39 |
| 12 |
|
Os Belenenses | 33 | 11 | 6 | 16 | 40:41 | -1 | 39 |
| 13 |
|
Académica de Coimbra | 33 | 10 | 8 | 15 | 35:46 | -11 | 38 |
| 14 |
|
Gil Vicente | 33 | 10 | 7 | 16 | 36:42 | -6 | 37 |
| 15 |
|
Naval 1° de Maio | 33 | 10 | 6 | 17 | 34:48 | -14 | 36 |
| 16 |
|
Vitória Guimarães | 33 | 8 | 10 | 15 | 28:40 | -12 | 34 |
| 17 |
|
Rio Ave FC | 33 | 8 | 10 | 15 | 32:48 | -16 | 34 |
| 18 |
|
FC Penafiel | 33 | 2 | 9 | 22 | 21:60 | -39 | 15 |
| Champions League | |
| Champions League Kwali. | |
| UEFA Cup | |
| Degradatie |
