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| 04.11.2022 | 19:00 | FC-Astoria Walldorf | - | TSV Steinbach Haiger | 0:6 (0:5) | |
| 05.11.2022 | 14:00 | SG Barockstadt Fulda-Lehnerz | - | FSV Frankfurt | 2:1 (1:1) | |
| 14:00 | VfB Stuttgart II | - | SSV Ulm 1846 | 0:0 (0:0) | ||
| 14:00 | Kickers Offenbach | - | 1. FSV Mainz 05 II | 1:1 (0:1) | ||
| 14:00 | Hessen Kassel | - | Bahlinger SC | 3:2 (1:1) | ||
| 14:00 | FC 08 Homburg | - | Eintracht Trier | 1:1 (0:0) | ||
| 14:00 | TSG Balingen | - | Wormatia Worms | 1:0 (1:0) | ||
| 14:00 | VfR Aalen | - | 1899 Hoffenheim II | 0:1 (0:0) | ||
| 14:00 | SGV Freiberg | - | Rot-Weiß Koblenz | 0:0 (0:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SSV Ulm 1846 | 15 | 10 | 4 | 1 | 27:9 | 18 | 34 |
| 2 |
|
TSV Steinbach Haiger | 15 | 10 | 1 | 4 | 37:17 | 20 | 31 |
| 3 |
|
1899 Hoffenheim II | 15 | 9 | 2 | 4 | 35:25 | 10 | 29 |
| 4 |
|
FC 08 Homburg | 15 | 8 | 2 | 5 | 29:20 | 9 | 26 |
| 5 |
|
1. FSV Mainz 05 II | 15 | 8 | 2 | 5 | 28:20 | 8 | 26 |
| 6 |
|
TSG Balingen | 15 | 7 | 5 | 3 | 22:16 | 6 | 26 |
| 7 |
|
Kickers Offenbach | 15 | 7 | 4 | 4 | 28:17 | 11 | 25 |
| 8 |
|
SG Barockstadt Fulda-Lehnerz | 15 | 6 | 6 | 3 | 25:18 | 7 | 24 |
| 9 |
|
VfB Stuttgart II | 15 | 5 | 6 | 4 | 20:19 | 1 | 21 |
| 10 |
|
Bahlinger SC | 15 | 7 | 0 | 8 | 18:25 | -7 | 21 |
| 11 |
|
FSV Frankfurt | 15 | 6 | 2 | 7 | 22:24 | -2 | 20 |
| 12 |
|
SGV Freiberg | 15 | 3 | 6 | 6 | 17:24 | -7 | 15 |
| 13 |
|
Wormatia Worms | 15 | 4 | 3 | 8 | 14:22 | -8 | 15 |
| 14 |
|
FC-Astoria Walldorf | 15 | 4 | 3 | 8 | 21:36 | -15 | 15 |
| 15 |
|
Eintracht Trier | 15 | 3 | 4 | 8 | 15:26 | -11 | 13 |
| 16 |
|
Hessen Kassel | 15 | 3 | 3 | 9 | 14:27 | -13 | 12 |
| 17 |
|
Rot-Weiß Koblenz | 15 | 1 | 4 | 10 | 10:31 | -21 | 7 |
| 18 |
|
VfR Aalen | 15 | 4 | 3 | 8 | 19:25 | -6 | 6 |
| Promotie | |
| Degradatie |
