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| 22.09.2018 | 10:30 | Enisey Krasnoyarsk | - | FK Ural | 1:2 (0:1) | |
| 13:00 | Dinamo Moskou | - | Anzhi Makhachkala | 0:1 (0:0) | ||
| 15:30 | Arsenal Tula | - | Rubin Kazan | 2:2 (1:0) | ||
| 18:00 | FK Rostov | - | FK Ufa | 0:0 (0:0) | ||
| 18:00 | Akhmat Grozny | - | FK Orenburg | 1:1 (1:0) | ||
| 23.09.2018 | 15:30 | Zenit St. Petersburg | - | Lokomotiv Moskou | 5:3 (1:1) | |
| 18:00 | CSKA Moskou | - | Spartak Moskou | 1:1 (0:1) | ||
| 24.09.2018 | 17:30 | Krylia Sovetov | - | FK Krasnodar | 0:3 (0:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Zenit St. Petersburg | 8 | 7 | 1 | 0 | 17:5 | 12 | 22 |
| 2 |
|
FK Krasnodar | 8 | 5 | 1 | 2 | 14:6 | 8 | 16 |
| 3 |
|
FK Rostov | 8 | 4 | 3 | 1 | 9:3 | 6 | 15 |
| 4 |
|
Spartak Moskou | 8 | 4 | 3 | 1 | 7:4 | 3 | 15 |
| 5 |
|
CSKA Moskou | 8 | 3 | 4 | 1 | 13:4 | 9 | 13 |
| 6 |
|
FK Orenburg | 8 | 3 | 2 | 3 | 10:8 | 2 | 11 |
| 7 |
|
Rubin Kazan | 8 | 2 | 5 | 1 | 9:8 | 1 | 11 |
| 8 |
|
Akhmat Grozny | 8 | 3 | 2 | 3 | 9:10 | -1 | 11 |
| 9 |
|
Dinamo Moskou | 8 | 2 | 4 | 2 | 9:6 | 3 | 10 |
| 10 |
|
Arsenal Tula | 8 | 2 | 3 | 3 | 9:8 | 1 | 9 |
| 11 |
|
Lokomotiv Moskou | 8 | 2 | 3 | 3 | 8:10 | -2 | 9 |
| 12 |
|
FK Ural | 8 | 2 | 2 | 4 | 8:15 | -7 | 8 |
| 13 |
|
Krylia Sovetov | 8 | 2 | 1 | 5 | 2:12 | -10 | 7 |
| 14 |
|
Anzhi Makhachkala | 8 | 2 | 0 | 6 | 4:14 | -10 | 6 |
| 15 |
|
FK Ufa | 8 | 1 | 2 | 5 | 4:11 | -7 | 5 |
| 16 |
|
Enisey Krasnoyarsk | 8 | 1 | 2 | 5 | 3:11 | -8 | 5 |
| Champions League | |
| Champions League Kwali. | |
| Europa League | |
| Europa League Kwali. | |
| Promotie en degradatie | |
| Degradatie |
