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| 03.12.2021 | 12:00 | FK Strogino Moskva | - | Rubin Kazan | 0:1 (0:0) | |
| 12:00 | Krylia Sovetov | - | Dinamo Moskva | 1:2 (0:2) | ||
| 12:00 | FK Nizhny Novgorod | - | Akademiya Konopleva | 5:2 (2:0) | ||
| 12:00 | Spartak Moskva | - | CSKA Moskva | 0:1 (0:0) | ||
| 12:00 | FK Ural | - | FK Ufa | 4:1 (1:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CSKA Moskva | 18 | 13 | 1 | 4 | 40:15 | 25 | 40 |
| 2 |
|
Dinamo Moskva | 18 | 12 | 1 | 5 | 41:27 | 14 | 37 |
| 3 |
|
Spartak Moskva | 18 | 10 | 3 | 5 | 33:19 | 14 | 33 |
| 4 |
|
Krylia Sovetov | 18 | 10 | 3 | 5 | 25:23 | 2 | 33 |
| 5 |
|
Rubin Kazan | 18 | 7 | 5 | 6 | 38:31 | 7 | 26 |
| 6 |
|
FK Nizhny Novgorod | 18 | 7 | 2 | 9 | 26:32 | -6 | 23 |
| 7 |
|
FK Strogino Moskva | 18 | 6 | 3 | 9 | 26:22 | 4 | 21 |
| 8 |
|
FK Ural | 18 | 5 | 1 | 12 | 22:35 | -13 | 16 |
| 9 |
|
Akademiya Konopleva | 18 | 4 | 4 | 10 | 21:41 | -20 | 16 |
| 10 |
|
FK Ufa | 18 | 3 | 3 | 12 | 9:36 | -27 | 12 |
| Play-offs | |
| Promotie en degradatie |
