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| 21.10.2021 | 16:30 | FK Napredak | - | FK Novi Pazar | 1:1 (0:0) | |
| 22.10.2021 | 16:00 | Radnik Surdulica | - | FK Voždovac | 1:3 (1:1) | |
| 18:00 | FK Čukarički | - | Proleter Novi Sad | 6:1 (2:1) | ||
| 23.10.2021 | 15:00 | Mladost Lučani | - | FK Kolubara | 3:1 (1:1) | |
| 17:00 | Spartak Subotica | - | FK Metalac | 2:0 (1:0) | ||
| 24.10.2021 | 13:30 | TSC Bačka Topola | - | Partizan | 1:3 (1:3) | |
| 17:00 | Vojvodina | - | FK Radnički 1923 | 3:1 (0:1) | ||
| 18:45 | Rode Ster Belgrado | - | Radnički Niš | 1:0 (0:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Partizan | 14 | 13 | 1 | 0 | 42:5 | 37 | 40 |
| 2 |
|
Rode Ster Belgrado | 14 | 11 | 2 | 1 | 31:8 | 23 | 35 |
| 3 |
|
FK Čukarički | 14 | 7 | 5 | 2 | 25:15 | 10 | 26 |
| 4 |
|
Vojvodina | 14 | 6 | 5 | 3 | 19:14 | 5 | 23 |
| 5 |
|
TSC Bačka Topola | 14 | 6 | 2 | 6 | 24:21 | 3 | 20 |
| 6 |
|
FK Napredak | 14 | 6 | 2 | 6 | 17:15 | 2 | 20 |
| 7 |
|
FK Voždovac | 14 | 6 | 2 | 6 | 18:17 | 1 | 20 |
| 8 |
|
Spartak Subotica | 14 | 5 | 3 | 6 | 18:26 | -8 | 18 |
| 9 |
|
Radnički Niš | 14 | 4 | 5 | 5 | 16:19 | -3 | 17 |
| 10 |
|
Proleter Novi Sad | 14 | 5 | 2 | 7 | 13:26 | -13 | 17 |
| 11 |
|
Radnik Surdulica | 14 | 4 | 4 | 6 | 12:16 | -4 | 16 |
| 12 |
|
Mladost Lučani | 14 | 4 | 2 | 8 | 15:18 | -3 | 14 |
| 13 |
|
FK Radnički 1923 | 14 | 4 | 2 | 8 | 17:28 | -11 | 14 |
| 14 |
|
FK Kolubara | 14 | 4 | 1 | 9 | 16:33 | -17 | 13 |
| 15 |
|
FK Metalac | 14 | 3 | 3 | 8 | 18:24 | -6 | 12 |
| 16 |
|
FK Novi Pazar | 14 | 2 | 3 | 9 | 14:30 | -16 | 9 |
| Play-offs | |
| Promotie en degradatie |
