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| 12.03.2022 | 15:00 | FC Sion II | - | FC Chiasso | 0:1 (0:1) | |
| 15:30 | FC Basel II | - | FC Biel/Bienne | 1:3 (1:1) | ||
| 16:00 | FC Rapperswil-Jona | - | SC Cham | 1:1 (0:1) | ||
| 16:00 | SC Brühl | - | FC Bavois | 1:1 (0:1) | ||
| 16:00 | FC Zürich II | - | AC Bellinzona | 0:0 (0:0) | ||
| 16:00 | FC Breitenrain Bern | - | Stade Nyonnais | 2:0 (1:0) | ||
| 16:00 | SC YF/Juventus Zürich | - | FC Black Stars Basel | 0:0 (0:0) | ||
| 17:00 | Etoile Carouge FC | - | BSC Young Boys II | 2:0 (1:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Breitenrain Bern | 22 | 16 | 6 | 0 | 45:16 | 29 | 54 |
| 2 |
|
AC Bellinzona | 22 | 14 | 4 | 4 | 44:24 | 20 | 46 |
| 3 |
|
Stade Nyonnais | 22 | 12 | 4 | 6 | 52:32 | 20 | 40 |
| 4 |
|
FC Chiasso | 22 | 11 | 6 | 5 | 39:24 | 15 | 39 |
| 5 |
|
FC Zürich II | 22 | 8 | 8 | 6 | 33:24 | 9 | 32 |
| 6 |
|
BSC Young Boys II | 22 | 8 | 6 | 8 | 38:37 | 1 | 30 |
| 7 |
|
SC Cham | 22 | 8 | 6 | 8 | 34:36 | -2 | 30 |
| 8 |
|
FC Bavois | 22 | 8 | 5 | 9 | 32:35 | -3 | 29 |
| 9 |
|
Etoile Carouge FC | 22 | 7 | 8 | 7 | 25:29 | -4 | 29 |
| 10 |
|
FC Black Stars Basel | 22 | 7 | 7 | 8 | 27:34 | -7 | 28 |
| 11 |
|
FC Rapperswil-Jona | 22 | 7 | 6 | 9 | 29:36 | -7 | 27 |
| 12 |
|
FC Biel/Bienne | 22 | 7 | 5 | 10 | 32:35 | -3 | 26 |
| 13 |
|
SC YF/Juventus Zürich | 22 | 6 | 5 | 11 | 33:41 | -8 | 23 |
| 14 |
|
FC Basel II | 22 | 5 | 4 | 13 | 38:56 | -18 | 19 |
| 15 |
|
SC Brühl | 22 | 4 | 5 | 13 | 30:44 | -14 | 17 |
| 16 |
|
FC Sion II | 22 | 3 | 5 | 14 | 24:52 | -28 | 14 |
| Play-offs | |
| Play-offs | |
| Promotie en degradatie |
