| Ronde | Datum | Wedstrijd | Res. | Geel | Geel/Rood | Rood |
|---|---|---|---|---|---|---|
| 2. Ronde | 17.01.2021 | Pumas UNAM - Mazatlán FC | 3:0 | - | - | - |
| 4. Ronde | 31.01.2021 | Cruz Azul - Querétaro | 4:1 | 2 | - | - |
| 5. Ronde | 05.02.2021 | San Luis - Club Tijuana | 2:2 | 7 | - | - |
| 6. Ronde | 14.02.2021 | Toluca - Pumas UNAM | 1:0 | 4 | - | - |
| 7. Ronde | 20.02.2021 | Necaxa - CF Monterrey | 1:1 | 2 | - | - |
| 8. Ronde | 01.03.2021 | Santos Laguna - FC Juárez | 3:2 | 2 | - | - |
| 9. Ronde | 04.03.2021 | Cruz Azul - Mazatlán FC | 1:0 | 2 | - | 1 |
| 3. Ronde | 11.03.2021 | CF Monterrey - Club León | 1:1 | 4 | - | - |
| 12. Ronde | 21.03.2021 | Toluca - Puebla | 4:4 | 3 | 1 | - |
| 13. Ronde | 04.04.2021 | CF Monterrey - San Luis | 2:0 | 5 | - | - |
| 14. Ronde | 11.04.2021 | Atlas - Club León | 1:3 | 4 | - | - |
| 15. Ronde | 19.04.2021 | Santos Laguna - Toluca | 3:1 | 5 | - | 1 |
| 16. Ronde | 25.04.2021 | Cruz Azul - San Luis | 3:2 | 2 | - | - |
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