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| 06.05.2022 | 21:00 | Lille OSC | - | AS Monaco | 1:2 (0:1) | |
| 07.05.2022 | 17:00 | Stade Brestois | - | RC Strasbourg | 0:1 (0:0) | |
| 08.05.2022 | 13:00 | FC Metz | - | Olympique Lyon | 3:2 (2:1) | |
| 15:00 | Clermont Foot 63 | - | Montpellier HSC | 2:1 (1:1) | ||
| 15:00 | Angers SCO | - | Girondins Bordeaux | 4:1 (2:0) | ||
| 15:00 | Stade Reims | - | RC Lens | 1:2 (1:0) | ||
| 17:05 | FC Lorient | - | Olympique Marseille | 0:3 (0:1) | ||
| 20:45 | Paris Saint-Germain | - | ESTAC Troyes | 2:2 (2:1) | ||
| 11.05.2022 | 19:00 | OGC Nice | - | AS Saint-Étienne | 4:2 (0:2) | |
| 21:00 | FC Nantes | - | Stade Rennais | 2:1 (1:1) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Paris Saint-Germain | 36 | 24 | 8 | 4 | 81:36 | 45 | 80 |
| 2 |
|
Olympique Marseille | 36 | 20 | 8 | 8 | 59:36 | 23 | 68 |
| 3 |
|
AS Monaco | 36 | 19 | 8 | 9 | 59:36 | 23 | 65 |
| 4 |
|
OGC Nice | 36 | 19 | 7 | 10 | 48:31 | 17 | 63 |
| 5 |
|
Stade Rennais | 36 | 19 | 5 | 12 | 78:38 | 40 | 62 |
| 6 |
|
RC Strasbourg | 36 | 16 | 12 | 8 | 59:39 | 20 | 60 |
| 7 |
|
RC Lens | 36 | 16 | 10 | 10 | 57:45 | 12 | 58 |
| 8 |
|
Olympique Lyon | 36 | 15 | 11 | 10 | 61:48 | 13 | 55 |
| 9 |
|
FC Nantes | 36 | 15 | 9 | 12 | 52:44 | 8 | 54 |
| 10 |
|
Lille OSC | 36 | 13 | 12 | 11 | 43:45 | -2 | 51 |
| 11 |
|
Stade Brestois | 36 | 13 | 9 | 14 | 45:49 | -4 | 48 |
| 12 |
|
Stade Reims | 36 | 10 | 13 | 13 | 39:40 | -1 | 43 |
| 13 |
|
Montpellier HSC | 36 | 12 | 7 | 17 | 49:55 | -6 | 43 |
| 14 |
|
Angers SCO | 36 | 9 | 11 | 16 | 42:54 | -12 | 38 |
| 15 |
|
ESTAC Troyes | 36 | 9 | 10 | 17 | 35:49 | -14 | 37 |
| 16 |
|
Clermont Foot 63 | 36 | 9 | 9 | 18 | 37:66 | -29 | 36 |
| 17 |
|
FC Lorient | 36 | 8 | 10 | 18 | 34:62 | -28 | 34 |
| 18 |
|
AS Saint-Étienne | 36 | 7 | 10 | 19 | 40:74 | -34 | 31 |
| 19 |
|
FC Metz | 36 | 5 | 13 | 18 | 34:64 | -30 | 28 |
| 20 |
|
Girondins Bordeaux | 36 | 5 | 12 | 19 | 48:89 | -41 | 27 |
| Champions League | |
| Champions League Kwali. | |
| Europa League | |
| Promotie en degradatie | |
| Degradatie |
