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| 17.02.2006 | 20:30 | Amiens SC | - | Stade Brestois | 1:1 (1:0) | |
| 20:30 | Clermont Foot Auvergne | - | SC Bastia | 2:0 (1:0) | ||
| 20:30 | EA Guingamp | - | US Créteil-Lusitanos | 0:0 (0:0) | ||
| 20:30 | FC Istres | - | Grenoble Foot 38 | 2:1 (0:0) | ||
| 20:30 | Stade Lavallois | - | Havre AC | 0:0 (0:0) | ||
| 20:30 | FC Lorient | - | Dijon FCO | 1:0 (0:0) | ||
| 20:30 | Stade Reims | - | Montpellier HSC | 0:1 (0:0) | ||
| 20:30 | CS Sedan | - | SM Caen | 1:1 (1:1) | ||
| 20:30 | FC Sète | - | FC Gueugnon | 2:0 (0:0) | ||
| 20:30 | Valenciennes FC | - | LB Châteauroux | 2:0 (2:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SC Bastia | 26 | 14 | 7 | 5 | 37:19 | 18 | 49 |
| 2 |
|
CS Sedan | 26 | 13 | 10 | 3 | 37:22 | 15 | 49 |
| 3 |
|
FC Lorient | 26 | 12 | 9 | 5 | 32:18 | 14 | 45 |
| 4 |
|
Valenciennes FC | 26 | 12 | 9 | 5 | 33:21 | 12 | 45 |
| 5 |
|
Dijon FCO | 26 | 10 | 9 | 7 | 29:24 | 5 | 39 |
| 6 |
|
US Créteil-Lusitanos | 26 | 9 | 11 | 6 | 34:20 | 14 | 38 |
| 7 |
|
Montpellier HSC | 26 | 9 | 9 | 8 | 24:26 | -2 | 36 |
| 8 |
|
SM Caen | 26 | 8 | 11 | 7 | 31:26 | 5 | 35 |
| 9 |
|
Havre AC | 26 | 7 | 12 | 7 | 30:29 | 1 | 33 |
| 10 |
|
FC Gueugnon | 26 | 7 | 12 | 7 | 17:25 | -8 | 33 |
| 11 |
|
LB Châteauroux | 26 | 7 | 11 | 8 | 30:31 | -1 | 32 |
| 12 |
|
Grenoble Foot 38 | 26 | 8 | 8 | 10 | 25:30 | -5 | 32 |
| 13 |
|
Stade Reims | 26 | 6 | 13 | 7 | 21:17 | 4 | 31 |
| 14 |
|
Amiens SC | 26 | 6 | 13 | 7 | 25:26 | -1 | 31 |
| 15 |
|
Stade Brestois | 26 | 7 | 9 | 10 | 24:29 | -5 | 30 |
| 16 |
|
FC Istres | 26 | 7 | 9 | 10 | 24:35 | -11 | 30 |
| 17 |
|
Clermont Foot Auvergne | 26 | 7 | 7 | 12 | 22:40 | -18 | 28 |
| 18 |
|
EA Guingamp | 26 | 5 | 12 | 9 | 17:20 | -3 | 27 |
| 19 |
|
Stade Lavallois | 26 | 6 | 5 | 15 | 20:36 | -16 | 23 |
| 20 |
|
FC Sète | 26 | 3 | 8 | 15 | 21:39 | -18 | 17 |
