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| U | Manchester City WFC | - | Linköpings FC | 2:0 (1:0) | ||
| R | Linköpings FC | - | Manchester City WFC | 3:5 (0:4) | ||
| U: 21.03.2018 20:00 | R: 28.03.2018 18:00 | Winnaars: Manchester City WFC | ||||
| U | Montpellier HSC | - | Chelsea LFC | 0:2 (0:0) | ||
| R | Chelsea LFC | - | Montpellier HSC | 3:1 (1:1) | ||
| U: 21.03.2018 20:45 | R: 28.03.2018 20:05 | Winnaars: Chelsea LFC | ||||
| U | VfL Wolfsburg | - | Slavia Praag | 5:0 (3:0) | ||
| R | Slavia Praag | - | VfL Wolfsburg | 1:1 (1:0) | ||
| U: 22.03.2018 18:00 | R: 28.03.2018 18:00 | Winnaars: VfL Wolfsburg | ||||
| U | Olympique Lyon | - | FC Barcelona | 2:1 (1:0) | ||
| R | FC Barcelona | - | Olympique Lyon | 0:1 (0:0) | ||
| U: 22.03.2018 18:45 | R: 28.03.2018 19:00 | Winnaars: Olympique Lyon | ||||
