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| 06.02.2022 | 14:30 | Foligno Calcio | - | FC Rieti | 2:2 | |
| 14:30 | Follonica Gavorrano | - | Montespaccato | 2:1 | ||
| 14:30 | US Pianese | - | Cascina | 3:2 | ||
| 14:30 | Pro Livorno Sorgenti | - | ASD Cannara | 3:1 | ||
| 14:30 | San Donato Tavarnelle | - | Badesse Calcio | 5:0 | ||
| 14:30 | AC Sangiovannese | - | SC Trestina | 0:2 | ||
| 14:30 | SSD Tiferno Lerchi | - | Virtus Flaminia | 4:4 | ||
| 14:30 | US Arezzo | - | Unipomezia Virtus | 3:0 | ||
| 14:30 | US Poggibonsi | - | Scandicci Calcio | 2:0 |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
San Donato Tavarnelle | 19 | 15 | 2 | 2 | 56:19 | 37 | 47 |
| 2 |
|
US Poggibonsi | 19 | 13 | 4 | 2 | 31:11 | 20 | 43 |
| 3 |
|
Follonica Gavorrano | 19 | 10 | 7 | 2 | 32:15 | 17 | 37 |
| 4 |
|
US Arezzo | 19 | 9 | 6 | 4 | 35:28 | 7 | 33 |
| 5 |
|
SC Trestina | 19 | 9 | 5 | 5 | 26:16 | 10 | 32 |
| 6 |
|
Badesse Calcio | 19 | 8 | 6 | 5 | 27:26 | 1 | 30 |
| 7 |
|
US Pianese | 19 | 7 | 6 | 6 | 29:27 | 2 | 27 |
| 8 |
|
Virtus Flaminia | 19 | 7 | 5 | 7 | 33:32 | 1 | 26 |
| 9 |
|
SSD Tiferno Lerchi | 19 | 6 | 8 | 5 | 25:27 | -2 | 26 |
| 10 |
|
Montespaccato | 19 | 7 | 4 | 8 | 28:25 | 3 | 25 |
| 11 |
|
AC Sangiovannese | 19 | 6 | 6 | 7 | 27:27 | 0 | 24 |
| 12 |
|
Scandicci Calcio | 19 | 6 | 4 | 9 | 18:26 | -8 | 22 |
| 13 |
|
Foligno Calcio | 19 | 5 | 6 | 8 | 29:36 | -7 | 21 |
| 14 |
|
ASD Cannara | 19 | 4 | 5 | 10 | 15:25 | -10 | 17 |
| 15 |
|
Unipomezia Virtus | 19 | 4 | 5 | 10 | 22:39 | -17 | 17 |
| 16 |
|
Cascina | 19 | 3 | 5 | 11 | 17:28 | -11 | 14 |
| 17 |
|
FC Rieti | 19 | 3 | 5 | 11 | 19:37 | -18 | 14 |
| 18 |
|
Pro Livorno Sorgenti | 19 | 3 | 3 | 13 | 20:45 | -25 | 12 |
| Promotie | |
| Play-offs | |
| Promotie en degradatie | |
| Degradatie |
