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| 02.04.2010 | 16:00 | FC Mondercange | - | Progrès Niedercorn | 4:3 d.p. | |
| 20:00 | Etzella Ettelbruck | - | CS Pétange | 2:1 n.v. | ||
| 03.04.2010 | 16:00 | CS Obercorn | - | FC Differdange 03 | 0:3 | |
| 16:00 | Young Boys Diekirch | - | Swift Hesperange | 1:2 | ||
| 16:00 | ES Clemency | - | CS Grevenmacher | 1:4 d.p. | ||
| 16:00 | RM Hamm Benfica | - | F91 Dudelange | 1:2 | ||
| 16:00 | CS FOLA Esch | - | UN Käerjéng | 4:2 d.p. | ||
| 16:00 | Jeunesse Canach | - | US Rumelange | 4:3 d.p. |
