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| 22.04.2023 | 17:00 | CF Pachuca | - | Deportivo Toluca | 0:5 (0:1) | |
| 19:15 | FC Juárez | - | CF América | 3:4 (2:1) | ||
| 19:30 | Atlas Guadalajara | - | Club Tijuana | 2:3 (0:1) | ||
| 19:30 | Cruz Azul | - | Club Necaxa | 1:2 (0:0) | ||
| 19:30 | Deportivo Guadalajara | - | UANL Tigres | 3:2 (1:0) | ||
| 19:30 | CF Monterrey | - | Mazatlán FC | 3:1 (2:0) | ||
| 19:45 | Atlético San Luis | - | Santos Laguna | 0:1 (0:0) | ||
| 20:30 | Gallos Blancos | - | Puebla FC | 2:2 (1:2) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| 1 | |||||||||
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Club Necaxa | 14 | 12 | 1 | 1 | 35:9 | 26 | 37 |
| 2 |
|
CF América | 14 | 9 | 2 | 3 | 39:20 | 19 | 29 |
| 3 |
|
Pumas UNAM | 14 | 6 | 4 | 4 | 21:19 | 2 | 22 |
| 4 |
|
Cruz Azul | 14 | 5 | 5 | 4 | 24:23 | 1 | 20 |
| 5 |
|
CF Pachuca | 14 | 5 | 4 | 5 | 22:24 | -2 | 19 |
| 6 |
|
Deportivo Toluca | 14 | 5 | 2 | 7 | 16:17 | -1 | 17 |
| 7 |
|
Puebla FC | 14 | 5 | 2 | 7 | 25:32 | -7 | 17 |
| 8 |
|
Gallos Blancos | 15 | 3 | 3 | 9 | 12:21 | -9 | 12 |
| 9 |
|
FC Juárez | 15 | 1 | 3 | 11 | 13:42 | -29 | 6 |
| 2 | |||||||||
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF Monterrey | 14 | 11 | 1 | 2 | 35:18 | 17 | 34 |
| 2 |
|
Santos Laguna | 14 | 10 | 2 | 2 | 34:14 | 20 | 32 |
| 3 |
|
Club Tijuana | 14 | 8 | 5 | 1 | 41:14 | 27 | 29 |
| 4 |
|
Deportivo Guadalajara | 15 | 6 | 3 | 6 | 25:34 | -9 | 21 |
| 5 |
|
Club León | 14 | 5 | 3 | 6 | 23:27 | -4 | 18 |
| 6 |
|
Atlas Guadalajara | 14 | 5 | 2 | 7 | 25:26 | -1 | 17 |
| 7 |
|
UANL Tigres | 15 | 3 | 4 | 8 | 31:37 | -6 | 13 |
| 8 |
|
Mazatlán FC | 14 | 2 | 2 | 10 | 12:38 | -26 | 8 |
| 9 |
|
Atlético San Luis | 14 | 1 | 4 | 9 | 14:32 | -18 | 7 |
| Play-offs | |
| Play-offs |
