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| U | CF Monterrey | - | CF América | 1:0 (0:0) | ||
| R | CF América | - | CF Monterrey | 1:1 (1:0) | ||
| U: 22.11.2009 00:00 | R: 29.11.2009 04:00 | Winnaars: CF Monterrey | ||||
| U | Puebla FC | - | Cruz Azul | 4:4 (4:2) | ||
| R | Cruz Azul | - | Puebla FC | 3:2 (2:1) | ||
| U: 22.11.2009 02:00 | R: 29.11.2009 00:00 | Winnaars: Cruz Azul | ||||
| U | Club San Luis | - | Deportivo Toluca | 1:0 (0:0) | ||
| R | Deportivo Toluca | - | Club San Luis | 1:0 (0:0) | ||
| U: 22.11.2009 19:00 | R: 29.11.2009 19:00 | |||||
| U | Santos Laguna | - | Monarcas Morelia | 2:1 (1:0) | ||
| R | Monarcas Morelia | - | Santos Laguna | 3:0 (2:0) | ||
| U: 23.11.2009 00:00 | R: 30.11.2009 00:00 | Winnaars: Monarcas Morelia | ||||
