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| 11.12.2015 | 20:00 | FC Volendam | - | TOP Oss | 1:1 (1:0) | |
| 20:00 | FC Dordrecht | - | Sparta Rotterdam | 0:3 (0:1) | ||
| 20:00 | NAC Breda | - | Go Ahead Eagles | 0:1 (0:0) | ||
| 20:00 | Jong PSV | - | Almere City FC | 3:4 (1:2) | ||
| 20:00 | MVV Maastricht | - | RKC Waalwijk | 6:2 (3:0) | ||
| 20:00 | FC Den Bosch | - | Jong Ajax | 3:0 (3:0) | ||
| 20:00 | Fortuna Sittard | - | FC Emmen | 2:2 (1:1) | ||
| 20:00 | VVV-Venlo | - | Achilles'29 | 3:0 (2:0) | ||
| 20:00 | Helmond Sport | - | Telstar | 4:1 (2:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Sparta Rotterdam | 17 | 12 | 3 | 2 | 40:19 | 21 | 39 |
| 2 |
|
VVV-Venlo | 17 | 10 | 4 | 3 | 36:14 | 22 | 34 |
| 3 |
|
FC Volendam | 17 | 9 | 4 | 4 | 33:16 | 17 | 31 |
| 4 |
|
Go Ahead Eagles | 17 | 10 | 1 | 6 | 32:20 | 12 | 31 |
| 5 |
|
NAC Breda | 17 | 9 | 3 | 5 | 38:18 | 20 | 30 |
| 6 |
|
FC Eindhoven | 17 | 9 | 3 | 5 | 27:22 | 5 | 30 |
| 7 |
|
FC Emmen | 17 | 7 | 4 | 6 | 32:27 | 5 | 25 |
| 8 |
|
MVV Maastricht | 17 | 7 | 4 | 6 | 31:28 | 3 | 25 |
| 9 |
|
FC Dordrecht | 17 | 7 | 3 | 7 | 25:28 | -3 | 24 |
| 10 |
|
Helmond Sport | 17 | 6 | 5 | 6 | 26:25 | 1 | 23 |
| 11 |
|
FC Den Bosch | 17 | 6 | 5 | 6 | 24:25 | -1 | 23 |
| 12 |
|
Telstar | 18 | 5 | 5 | 8 | 26:33 | -7 | 20 |
| 13 |
|
Jong Ajax | 17 | 4 | 6 | 7 | 25:31 | -6 | 18 |
| 14 |
|
Jong PSV | 17 | 4 | 6 | 7 | 23:38 | -15 | 18 |
| 15 |
|
Achilles'29 | 17 | 4 | 5 | 8 | 18:27 | -9 | 17 |
| 16 |
|
TOP Oss | 17 | 4 | 5 | 8 | 19:30 | -11 | 17 |
| 17 |
|
Fortuna Sittard | 17 | 4 | 3 | 10 | 19:45 | -26 | 15 |
| 18 |
|
Almere City FC | 17 | 3 | 5 | 9 | 28:40 | -12 | 14 |
| 19 |
|
RKC Waalwijk | 17 | 3 | 4 | 10 | 16:32 | -16 | 13 |
| Promotie | |
| Play-offs | |
| Play-offs | |
| Play-offs |
