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| 16.03.2018 | 23:00 | Rosario Central | - | Chacarita Juniors | 3:1 (1:1) | |
| 17.03.2018 | 01:15 | Colón de Santa Fe | - | Lanús | 1:2 (1:0) | |
| 17:15 | Argentinos Juniors | - | Newell's Old Boys | 1:0 (1:0) | ||
| 17:15 | Temperley | - | Huracán | 1:2 (0:1) | ||
| 19:30 | San Martín de San Juan | - | Gimnasia de La Plata | 3:0 (2:0) | ||
| 21:45 | San Lorenzo | - | Olimpo de Bahía Blanca | 2:0 (0:0) | ||
| 18.03.2018 | 00:00 | Talleres de Córdoba | - | Defensa y Justicia | 1:0 (1:0) | |
| 15:00 | Racing Club | - | Patronato de Paraná | 5:0 (3:0) | ||
| 17:15 | Arsenal de Sarandí | - | Vélez Sarsfield | 1:1 (1:1) | ||
| 19:30 | Estudiantes | - | Godoy Cruz | 0:1 (0:1) | ||
| 21:45 | Atlético Tucumán | - | Boca Juniors | 1:1 (1:0) | ||
| 19.03.2018 | 00:00 | River Plate | - | Belgrano de Córdoba | 3:1 (1:0) | |
| 23:00 | Banfield | - | Unión de Santa Fe | 0:2 (0:2) | ||
| 20.03.2018 | 01:15 | Tigre | - | Independiente | 1:1 (0:1) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Boca Juniors | 20 | 15 | 2 | 3 | 37:12 | 25 | 47 |
| 2 |
|
Talleres de Córdoba | 20 | 12 | 5 | 3 | 27:9 | 18 | 41 |
| 3 |
|
San Lorenzo | 20 | 11 | 6 | 3 | 24:11 | 13 | 39 |
| 4 |
|
Godoy Cruz | 20 | 11 | 4 | 5 | 28:21 | 7 | 37 |
| 5 |
|
Independiente | 20 | 10 | 6 | 4 | 23:13 | 10 | 36 |
| 6 |
|
Racing Club | 20 | 10 | 5 | 5 | 35:21 | 14 | 35 |
| 7 |
|
Unión de Santa Fe | 20 | 9 | 7 | 4 | 24:14 | 10 | 34 |
| 8 |
|
Huracán | 20 | 9 | 6 | 5 | 24:18 | 6 | 33 |
| 9 |
|
Colón de Santa Fe | 20 | 8 | 7 | 5 | 22:17 | 5 | 31 |
| 10 |
|
Estudiantes | 20 | 9 | 4 | 7 | 19:15 | 4 | 31 |
| 11 |
|
Argentinos Juniors | 20 | 9 | 3 | 8 | 27:24 | 3 | 30 |
| 12 |
|
Belgrano de Córdoba | 20 | 7 | 9 | 4 | 19:19 | 0 | 30 |
| 13 |
|
Defensa y Justicia | 20 | 8 | 5 | 7 | 29:26 | 3 | 29 |
| 14 |
|
Rosario Central | 20 | 7 | 7 | 6 | 26:25 | 1 | 28 |
| 15 |
|
Atlético Tucumán | 20 | 6 | 8 | 6 | 21:20 | 1 | 26 |
| 16 |
|
River Plate | 20 | 7 | 5 | 8 | 25:25 | 0 | 26 |
| 17 |
|
Banfield | 20 | 7 | 4 | 9 | 20:20 | 0 | 25 |
| 18 |
|
San Martín de San Juan | 20 | 7 | 4 | 9 | 22:28 | -6 | 25 |
| 19 |
|
Patronato de Paraná | 20 | 6 | 6 | 8 | 20:25 | -5 | 24 |
| 20 |
|
Vélez Sarsfield | 20 | 6 | 5 | 9 | 17:24 | -7 | 23 |
| 21 |
|
Lanús | 20 | 6 | 5 | 9 | 17:32 | -15 | 23 |
| 22 |
|
Gimnasia de La Plata | 20 | 6 | 4 | 10 | 20:30 | -10 | 22 |
| 23 |
|
Newell's Old Boys | 20 | 5 | 5 | 10 | 16:19 | -3 | 17 |
| 24 |
|
Tigre | 20 | 2 | 10 | 8 | 15:23 | -8 | 16 |
| 25 |
|
Temperley | 20 | 3 | 6 | 11 | 11:31 | -20 | 15 |
| 26 |
|
Chacarita Juniors | 20 | 3 | 5 | 12 | 16:27 | -11 | 14 |
| 27 |
|
Arsenal de Sarandí | 20 | 2 | 6 | 12 | 12:23 | -11 | 12 |
| 28 |
|
Olimpo de Bahía Blanca | 20 | 3 | 3 | 14 | 11:35 | -24 | 12 |
| Copa Libertadores | |
| Copa Sudamericana |
