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| 23.04.2011 | 18:00 | Valencia CF | - | Real Madrid | 3:6 (0:4) | |
| 20:00 | FC Barcelona | - | CA Osasuna | 2:0 (1:0) | ||
| 22:00 | Athletic Bilbao | - | Real Sociedad | 2:1 (2:1) | ||
| 24.04.2011 | 17:00 | RCD Mallorca | - | Getafe CF | 2:0 (1:0) | |
| 17:00 | Sporting Gijón | - | Espanyol | 1:0 (0:0) | ||
| 17:00 | Hércules CF | - | Deportivo La Coruña | 1:0 (0:0) | ||
| 17:00 | Racing Santander | - | Málaga CF | 1:2 (0:2) | ||
| 19:00 | Atlético Madrid | - | Levante UD | 4:1 (1:1) | ||
| 21:00 | Sevilla FC | - | Villarreal CF | 3:2 (2:0) | ||
| 25.04.2011 | 21:00 | Real Zaragoza | - | UD Almería | 1:0 (0:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Barcelona | 33 | 28 | 4 | 1 | 88:17 | 71 | 88 |
| 2 |
|
Real Madrid | 33 | 25 | 5 | 3 | 79:26 | 53 | 80 |
| 3 |
|
Valencia CF | 33 | 19 | 6 | 8 | 57:41 | 16 | 63 |
| 4 |
|
Villarreal CF | 33 | 17 | 6 | 10 | 51:39 | 12 | 57 |
| 5 |
|
Athletic Bilbao | 33 | 16 | 3 | 14 | 51:47 | 4 | 51 |
| 6 |
|
Sevilla FC | 33 | 14 | 7 | 12 | 51:49 | 2 | 49 |
| 7 |
|
Atlético Madrid | 33 | 14 | 7 | 12 | 54:44 | 10 | 49 |
| 8 |
|
Espanyol | 33 | 14 | 3 | 16 | 40:46 | -6 | 45 |
| 9 |
|
RCD Mallorca | 33 | 12 | 6 | 15 | 35:45 | -10 | 42 |
| 10 |
|
Levante UD | 33 | 12 | 6 | 15 | 37:46 | -9 | 42 |
| 11 |
|
Sporting Gijón | 33 | 10 | 11 | 12 | 31:37 | -6 | 41 |
| 12 |
|
Real Sociedad | 33 | 12 | 2 | 19 | 43:57 | -14 | 38 |
| 13 |
|
Deportivo La Coruña | 33 | 9 | 11 | 13 | 27:41 | -14 | 38 |
| 14 |
|
Getafe CF | 33 | 10 | 7 | 16 | 43:53 | -10 | 37 |
| 15 |
|
Racing Santander | 33 | 9 | 10 | 14 | 32:49 | -17 | 37 |
| 16 |
|
Málaga CF | 33 | 10 | 6 | 17 | 44:63 | -19 | 36 |
| 17 |
|
Real Zaragoza | 33 | 9 | 9 | 15 | 32:45 | -13 | 36 |
| 18 |
|
CA Osasuna | 33 | 9 | 8 | 16 | 37:41 | -4 | 35 |
| 19 |
|
Hércules CF | 33 | 9 | 6 | 18 | 30:50 | -20 | 33 |
| 20 |
|
UD Almería | 33 | 5 | 11 | 17 | 32:58 | -26 | 26 |
| Champions League | |
| Champions League Kwali. | |
| Europa League | |
| Degradatie |
