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| 05.02.2021 | 21:00 | Deportivo Alavés | - | Real Valladolid | 1:0 (0:0) | |
| 06.02.2021 | 14:00 | Levante UD | - | Granada CF | 2:2 (1:1) | |
| 16:15 | SD Huesca | - | Real Madrid | 1:2 (0:0) | ||
| 18:30 | Elche CF | - | Villarreal CF | 2:2 (0:2) | ||
| 21:00 | Sevilla FC | - | Getafe CF | 3:0 (0:0) | ||
| 07.02.2021 | 14:00 | Real Sociedad | - | Cádiz CF | 4:1 (2:0) | |
| 16:15 | Athletic Bilbao | - | Valencia CF | 1:1 (1:0) | ||
| 18:30 | CA Osasuna | - | SD Eibar | 2:1 (1:1) | ||
| 21:00 | Real Betis | - | FC Barcelona | 2:3 (1:0) | ||
| 08.02.2021 | 21:00 | Atlético Madrid | - | Celta de Vigo | 2:2 (1:1) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Atlético Madrid | 22 | 17 | 4 | 1 | 45:14 | 31 | 55 |
| 2 |
|
FC Barcelona | 22 | 14 | 4 | 4 | 47:20 | 27 | 46 |
| 3 |
|
Real Madrid | 22 | 14 | 4 | 4 | 39:19 | 20 | 46 |
| 4 |
|
Sevilla FC | 22 | 14 | 3 | 5 | 33:16 | 17 | 45 |
| 5 |
|
Villarreal CF | 22 | 8 | 12 | 2 | 31:22 | 9 | 36 |
| 6 |
|
Real Sociedad | 22 | 9 | 8 | 5 | 36:20 | 16 | 35 |
| 7 |
|
Real Betis | 22 | 9 | 3 | 10 | 29:37 | -8 | 30 |
| 8 |
|
Granada CF | 22 | 8 | 6 | 8 | 26:36 | -10 | 30 |
| 9 |
|
Levante UD | 22 | 6 | 10 | 6 | 32:32 | 0 | 28 |
| 10 |
|
Celta de Vigo | 22 | 6 | 8 | 8 | 26:33 | -7 | 26 |
| 11 |
|
Athletic Bilbao | 22 | 7 | 4 | 11 | 29:28 | 1 | 25 |
| 12 |
|
Valencia CF | 22 | 5 | 9 | 8 | 28:30 | -2 | 24 |
| 13 |
|
Getafe CF | 22 | 6 | 6 | 10 | 17:28 | -11 | 24 |
| 14 |
|
Cádiz CF | 22 | 6 | 6 | 10 | 20:35 | -15 | 24 |
| 15 |
|
CA Osasuna | 22 | 5 | 7 | 10 | 21:31 | -10 | 22 |
| 16 |
|
Deportivo Alavés | 22 | 5 | 7 | 10 | 19:29 | -10 | 22 |
| 17 |
|
SD Eibar | 22 | 4 | 8 | 10 | 18:25 | -7 | 20 |
| 18 |
|
Real Valladolid | 22 | 4 | 8 | 10 | 21:33 | -12 | 20 |
| 19 |
|
Elche CF | 22 | 3 | 9 | 10 | 18:33 | -15 | 18 |
| 20 |
|
SD Huesca | 22 | 2 | 10 | 10 | 18:32 | -14 | 16 |
| Champions League | |
| Europa League | |
| Europa League Kwali. | |
| Degradatie |
