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| 18.02.2011 | 21:00 | Girona FC | - | AD Alcorcón | 3:1 (2:0) | |
| 19.02.2011 | 16:00 | Rayo Vallecano | - | Gimnàstic de Tarragona | 1:1 (0:1) | |
| 18:00 | Elche CF | - | FC Barcelona B | 2:1 (1:1) | ||
| 18:00 | FC Cartagena | - | CD Numancia | 1:0 (0:0) | ||
| 18:00 | Xerez CD | - | Córdoba CF | 1:3 (1:2) | ||
| 18:00 | Celta de Vigo | - | CD Tenerife | 1:0 (0:0) | ||
| 18:00 | UD Salamanca | - | SD Huesca | 1:1 (0:1) | ||
| 18:00 | UD Las Palmas | - | Villarreal CF B | 2:2 (1:1) | ||
| 18:00 | Albacete | - | Recreativo Huelva | 1:1 (0:0) | ||
| 20.02.2011 | 12:00 | Real Valladolid | - | Real Betis | 1:0 (1:0) | |
| 17:00 | SD Ponferradina | - | Granada CF | 0:0 (0:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Celta de Vigo | 25 | 14 | 9 | 2 | 46:20 | 26 | 51 |
| 2 |
|
Rayo Vallecano | 25 | 15 | 5 | 5 | 44:26 | 18 | 50 |
| 3 |
|
Real Betis | 25 | 14 | 4 | 7 | 47:27 | 20 | 46 |
| 4 |
|
Granada CF | 25 | 11 | 8 | 6 | 45:27 | 18 | 41 |
| 5 |
|
Villarreal CF B | 25 | 12 | 5 | 8 | 32:33 | -1 | 41 |
| 6 |
|
Xerez CD | 25 | 11 | 5 | 9 | 35:35 | 0 | 38 |
| 7 |
|
FC Cartagena | 25 | 11 | 5 | 9 | 34:35 | -1 | 38 |
| 8 |
|
Girona FC | 25 | 9 | 9 | 7 | 37:32 | 5 | 36 |
| 9 |
|
FC Barcelona B | 25 | 9 | 8 | 8 | 38:36 | 2 | 35 |
| 10 |
|
Elche CF | 25 | 8 | 11 | 6 | 25:23 | 2 | 35 |
| 11 |
|
CD Numancia | 25 | 10 | 3 | 12 | 35:34 | 1 | 33 |
| 12 |
|
AD Alcorcón | 25 | 10 | 3 | 12 | 33:35 | -2 | 33 |
| 13 |
|
Córdoba CF | 25 | 7 | 11 | 7 | 34:33 | 1 | 32 |
| 14 |
|
Real Valladolid | 25 | 9 | 5 | 11 | 32:33 | -1 | 32 |
| 15 |
|
SD Huesca | 25 | 6 | 12 | 7 | 18:23 | -5 | 30 |
| 16 |
|
Recreativo Huelva | 25 | 5 | 12 | 8 | 22:25 | -3 | 27 |
| 17 |
|
UD Las Palmas | 25 | 5 | 11 | 9 | 33:48 | -15 | 26 |
| 18 |
|
Gimnàstic de Tarragona | 25 | 5 | 10 | 10 | 19:26 | -7 | 25 |
| 19 |
|
UD Salamanca | 25 | 7 | 4 | 14 | 27:37 | -10 | 25 |
| 20 |
|
Albacete | 25 | 5 | 9 | 11 | 18:29 | -11 | 24 |
| 21 |
|
CD Tenerife | 25 | 5 | 9 | 11 | 25:39 | -14 | 24 |
| 22 |
|
SD Ponferradina | 25 | 3 | 10 | 12 | 18:41 | -23 | 19 |
| Promotie | |
| Play-offs | |
| Degradatie |
