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| 20.04.2019 | 13:00 | SpVgg Greuther Fürth | - | 1. FC Union Berlin | 1:1 (0:1) | |
| 13:00 | MSV Duisburg | - | SV Sandhausen | 2:2 (0:1) | ||
| 13:00 | Hamburger SV | - | Erzgebirge Aue | 1:1 (0:1) | ||
| 13:00 | Holstein Kiel | - | SC Paderborn 07 | 1:2 (0:0) | ||
| 21.04.2019 | 13:30 | Dynamo Dresden | - | 1. FC Köln | 3:0 (2:0) | |
| 13:30 | SV Darmstadt 98 | - | VfL Bochum | 0:0 (0:0) | ||
| 13:30 | Arminia Bielefeld | - | FC Ingolstadt 04 | 1:3 (0:1) | ||
| 13:30 | 1. FC Heidenheim 1846 | - | FC St. Pauli | 3:0 (3:0) | ||
| 13:30 | Jahn Regensburg | - | 1. FC Magdeburg | 1:0 (1:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
1. FC Köln | 30 | 18 | 5 | 7 | 75:39 | 36 | 59 |
| 2 |
|
Hamburger SV | 30 | 15 | 8 | 7 | 41:33 | 8 | 53 |
| 3 |
|
SC Paderborn 07 | 30 | 14 | 9 | 7 | 68:43 | 25 | 51 |
| 4 |
|
1. FC Union Berlin | 30 | 12 | 14 | 4 | 46:29 | 17 | 50 |
| 5 |
|
1. FC Heidenheim 1846 | 30 | 13 | 10 | 7 | 44:34 | 10 | 49 |
| 6 |
|
Holstein Kiel | 30 | 12 | 10 | 8 | 55:45 | 10 | 46 |
| 7 |
|
Jahn Regensburg | 30 | 11 | 12 | 7 | 44:42 | 2 | 45 |
| 8 |
|
FC St. Pauli | 30 | 13 | 6 | 11 | 40:46 | -6 | 45 |
| 9 |
|
VfL Bochum | 30 | 10 | 9 | 11 | 41:43 | -2 | 39 |
| 10 |
|
Arminia Bielefeld | 30 | 10 | 9 | 11 | 44:48 | -4 | 39 |
| 11 |
|
SpVgg Greuther Fürth | 30 | 9 | 11 | 10 | 33:48 | -15 | 38 |
| 12 |
|
SV Darmstadt 98 | 30 | 10 | 7 | 13 | 40:48 | -8 | 37 |
| 13 |
|
Dynamo Dresden | 30 | 9 | 9 | 12 | 36:42 | -6 | 36 |
| 14 |
|
Erzgebirge Aue | 30 | 9 | 6 | 15 | 36:42 | -6 | 33 |
| 15 |
|
SV Sandhausen | 30 | 7 | 10 | 13 | 37:43 | -6 | 31 |
| 16 |
|
1. FC Magdeburg | 30 | 5 | 12 | 13 | 30:44 | -14 | 27 |
| 17 |
|
FC Ingolstadt 04 | 30 | 6 | 8 | 16 | 34:51 | -17 | 26 |
| 18 |
|
MSV Duisburg | 30 | 5 | 9 | 16 | 32:56 | -24 | 24 |
| Promotie | |
| Promotie en degradatie | |
| Promotie en degradatie | |
| Degradatie |
