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| 20.03.2022 | 15:00 | Spvg Wesseling-Urfeld | - | FC Hennef 05 | 1:4 (0:2) | |
| 15:00 | VfL Alfter | - | VfL 08 Vichttal | 1:0 (1:0) | ||
| 15:00 | BC Viktoria Glesch-Paffendorf | - | 1. FC Düren | 0:1 (0:0) | ||
| 15:00 | Viktoria Arnoldsweiler | - | SpVg Frechen 20 | 2:1 (0:0) | ||
| 15:00 | SV 1914 Eilendorf | - | Borussia Freialdenhoven | 1:3 (0:1) | ||
| 15:00 | SV Bergisch Gladbach 09 | - | Blau-Weiß Friesdorf | 1:1 (0:1) | ||
| 15:00 | SV Breinig | - | Fortuna Köln II | 0:1 (0:1) | ||
| 15:30 | FC Pesch 1956 | - | SV Deutz 05 | 4:3 (2:1) | ||
| 15:30 | Siegburger SV 04 | - | FC Hürth | 0:1 (0:1) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
1. FC Düren | 22 | 17 | 4 | 1 | 63:13 | 50 | 55 |
| 2 |
|
FC Hennef 05 | 22 | 15 | 4 | 3 | 50:15 | 35 | 49 |
| 3 |
|
SV Bergisch Gladbach 09 | 22 | 14 | 6 | 2 | 53:14 | 39 | 48 |
| 4 |
|
SpVg Frechen 20 | 22 | 12 | 4 | 6 | 44:25 | 19 | 40 |
| 5 |
|
Borussia Freialdenhoven | 22 | 12 | 3 | 7 | 37:28 | 9 | 39 |
| 6 |
|
FC Pesch 1956 | 22 | 9 | 8 | 5 | 49:30 | 19 | 35 |
| 7 |
|
BC Viktoria Glesch-Paffendorf | 22 | 10 | 5 | 7 | 37:25 | 12 | 35 |
| 8 |
|
Siegburger SV 04 | 22 | 9 | 7 | 6 | 35:27 | 8 | 34 |
| 9 |
|
Viktoria Arnoldsweiler | 22 | 10 | 2 | 10 | 37:33 | 4 | 32 |
| 10 |
|
Blau-Weiß Friesdorf | 22 | 8 | 6 | 8 | 34:37 | -3 | 30 |
| 11 |
|
VfL Alfter | 22 | 9 | 3 | 10 | 36:40 | -4 | 30 |
| 12 |
|
VfL 08 Vichttal | 22 | 8 | 4 | 10 | 40:44 | -4 | 28 |
| 13 |
|
FC Hürth | 22 | 8 | 4 | 10 | 28:41 | -13 | 28 |
| 14 |
|
Fortuna Köln II | 22 | 5 | 5 | 12 | 28:42 | -14 | 20 |
| 15 |
|
SV 1914 Eilendorf | 22 | 5 | 2 | 15 | 20:44 | -24 | 17 |
| 16 |
|
SV Deutz 05 | 22 | 4 | 3 | 15 | 24:54 | -30 | 15 |
| 17 |
|
SV Breinig | 22 | 4 | 2 | 16 | 25:62 | -37 | 14 |
| 18 |
|
Spvg Wesseling-Urfeld | 22 | 3 | 0 | 19 | 18:84 | -66 | 9 |
| Play-offs | |
| Degradatie |
