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| 16.09.2022 | 20:30 | 1. FSV Mainz 05 | - | Hertha BSC | 1:1 (0:1) | |
| 17.09.2022 | 15:30 | Borussia Dortmund | - | FC Schalke 04 | 1:0 (0:0) | |
| 15:30 | Bayer Leverkusen | - | Werder Bremen | 1:1 (0:0) | ||
| 15:30 | FC Augsburg | - | Bayern München | 1:0 (0:0) | ||
| 15:30 | VfB Stuttgart | - | Eintracht Frankfurt | 1:3 (0:1) | ||
| 18:30 | Bor. Mönchengladbach | - | RB Leipzig | 3:0 (2:0) | ||
| 18.09.2022 | 15:30 | 1. FC Union Berlin | - | VfL Wolfsburg | 2:0 (0:0) | |
| 17:30 | VfL Bochum | - | 1. FC Köln | 1:1 (1:0) | ||
| 19:30 | 1899 Hoffenheim | - | SC Freiburg | 0:0 (0:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
1. FC Union Berlin | 7 | 5 | 2 | 0 | 15:4 | 11 | 17 |
| 2 |
|
Borussia Dortmund | 7 | 5 | 0 | 2 | 9:7 | 2 | 15 |
| 3 |
|
SC Freiburg | 7 | 4 | 2 | 1 | 10:5 | 5 | 14 |
| 4 |
|
1899 Hoffenheim | 7 | 4 | 1 | 2 | 12:7 | 5 | 13 |
| 5 |
|
Bayern München (M) | 7 | 3 | 3 | 1 | 19:6 | 13 | 12 |
| 6 |
|
Bor. Mönchengladbach | 7 | 3 | 3 | 1 | 10:5 | 5 | 12 |
| 7 |
|
Eintracht Frankfurt | 7 | 3 | 2 | 2 | 14:13 | 1 | 11 |
| 8 |
|
1. FSV Mainz 05 | 7 | 3 | 2 | 2 | 7:10 | -3 | 11 |
| 9 |
|
1. FC Köln | 7 | 2 | 4 | 1 | 11:8 | 3 | 10 |
| 10 |
|
Werder Bremen (N) | 7 | 2 | 3 | 2 | 13:12 | 1 | 9 |
| 11 |
|
FC Augsburg | 7 | 3 | 0 | 4 | 5:10 | -5 | 9 |
| 12 |
|
RB Leipzig (P) | 7 | 2 | 2 | 3 | 9:12 | -3 | 8 |
| 13 |
|
Hertha BSC | 7 | 1 | 3 | 3 | 7:9 | -2 | 6 |
| 14 |
|
FC Schalke 04 (N) | 7 | 1 | 3 | 3 | 8:14 | -6 | 6 |
| 15 |
|
Bayer Leverkusen | 7 | 1 | 2 | 4 | 9:12 | -3 | 5 |
| 16 |
|
VfB Stuttgart | 7 | 0 | 5 | 2 | 7:10 | -3 | 5 |
| 17 |
|
VfL Wolfsburg | 7 | 1 | 2 | 4 | 5:12 | -7 | 5 |
| 18 |
|
VfL Bochum | 7 | 0 | 1 | 6 | 5:19 | -14 | 1 |
| Champions League | |
| Europa League | |
| Promotie en degradatie | |
| Degradatie |
