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| 21.11.2020 | 13:00 | FC Schalke 04 II | - | Borussia Dortmund II | 1:5 (1:2) | |
| 14:00 | Alemannia Aachen | - | 1. FC Köln II | 0:0 (0:0) | ||
| 14:00 | Bor. Mönchengladbach II | - | SV Lippstadt 08 | 0:0 (0:0) | ||
| 14:00 | Fortuna Köln | - | FC Wegberg-Beeck | 2:2 (1:0) | ||
| 14:00 | Preußen Münster | - | Fortuna Düsseldorf II | 2:1 (2:0) | ||
| 14:00 | Rot-Weiß Oberhausen | - | Rot Weiss Ahlen | 1:1 (1:0) | ||
| 14:00 | SV Bergisch Gladbach 09 | - | Bonner SC | 2:0 (0:0) | ||
| 14:00 | SV 19 Straelen | - | SC Wiedenbrück | 0:4 (0:2) | ||
| 14:00 | VfB Homberg | - | Rot-Weiss Essen | 0:4 (0:3) | ||
| 14:00 | Wuppertaler SV | - | Sportfreunde Lotte | 2:0 (2:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Borussia Dortmund II | 15 | 11 | 4 | 0 | 41:12 | 29 | 37 |
| 2 |
|
Rot-Weiss Essen | 15 | 11 | 4 | 0 | 31:7 | 24 | 37 |
| 3 |
|
Preußen Münster | 15 | 10 | 2 | 3 | 26:12 | 14 | 32 |
| 4 |
|
Fortuna Düsseldorf II | 15 | 8 | 5 | 2 | 31:11 | 20 | 29 |
| 5 |
|
Fortuna Köln | 15 | 7 | 5 | 3 | 32:20 | 12 | 26 |
| 6 |
|
Bor. Mönchengladbach II | 15 | 7 | 3 | 5 | 26:20 | 6 | 24 |
| 7 |
|
1. FC Köln II | 15 | 6 | 6 | 3 | 20:15 | 5 | 24 |
| 8 |
|
Alemannia Aachen | 16 | 6 | 5 | 5 | 13:12 | 1 | 23 |
| 9 |
|
FC Schalke 04 II | 15 | 5 | 6 | 4 | 17:16 | 1 | 21 |
| 10 |
|
SV Rödinghausen | 15 | 5 | 5 | 5 | 17:15 | 2 | 20 |
| 11 |
|
SV 19 Straelen | 16 | 5 | 5 | 6 | 19:25 | -6 | 20 |
| 12 |
|
SC Wiedenbrück | 15 | 4 | 7 | 4 | 27:27 | 0 | 19 |
| 13 |
|
Wuppertaler SV | 16 | 5 | 3 | 8 | 17:24 | -7 | 18 |
| 14 |
|
FC Wegberg-Beeck | 15 | 4 | 5 | 6 | 18:21 | -3 | 17 |
| 15 |
|
SV Bergisch Gladbach 09 | 16 | 4 | 5 | 7 | 16:24 | -8 | 17 |
| 16 |
|
Rot-Weiß Oberhausen | 15 | 3 | 7 | 5 | 21:25 | -4 | 16 |
| 17 |
|
VfB Homberg | 16 | 4 | 1 | 11 | 14:32 | -18 | 13 |
| 18 |
|
SV Lippstadt 08 | 15 | 1 | 8 | 6 | 12:25 | -13 | 11 |
| 19 |
|
Bonner SC | 15 | 3 | 2 | 10 | 13:30 | -17 | 11 |
| 20 |
|
Sportfreunde Lotte | 15 | 2 | 4 | 9 | 16:35 | -19 | 10 |
| 21 |
|
Rot Weiss Ahlen | 15 | 1 | 4 | 10 | 15:34 | -19 | 7 |
| Promotie | |
| Degradatie |
