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| 30.07.2022 | 14:00 | 1. FC Bocholt | - | Fortuna Düsseldorf II | 1:2 (0:0) | |
| 14:00 | Rot Weiss Ahlen | - | Fortuna Köln | 1:1 (0:1) | ||
| 31.07.2022 | 14:00 | 1. FC Köln II | - | FC Schalke 04 II | 1:3 (1:1) | |
| 14:00 | Bor. Mönchengladbach II | - | Rot-Weiß Oberhausen | 3:3 (2:3) | ||
| 14:00 | Alemannia Aachen | - | 1. FC Düren | 2:2 (1:1) | ||
| 14:00 | SC Wiedenbrück | - | Preußen Münster | 0:1 (0:1) | ||
| 14:00 | SG Wattenscheid 09 | - | Wuppertaler SV | 1:4 (0:2) | ||
| 10.08.2022 | 18:00 | SV Lippstadt 08 | - | SV Rödinghausen | 2:0 (1:0) | |
| 19:30 | SV 19 Straelen | - | 1. FC Kaan-Marienborn | 0:1 (0:1) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Preußen Münster | 2 | 2 | 0 | 0 | 5:1 | 4 | 6 |
| 2 |
|
FC Schalke 04 II | 2 | 2 | 0 | 0 | 4:1 | 3 | 6 |
| 3 |
|
SV Lippstadt 08 | 2 | 2 | 0 | 0 | 3:0 | 3 | 6 |
| 4 |
|
1. FC Kaan-Marienborn | 2 | 2 | 0 | 0 | 3:1 | 2 | 6 |
| 5 |
|
1. FC Düren | 2 | 1 | 1 | 0 | 5:3 | 2 | 4 |
| 6 |
|
Rot-Weiß Oberhausen | 2 | 1 | 1 | 0 | 5:4 | 1 | 4 |
| 7 |
|
Rot Weiss Ahlen | 2 | 1 | 1 | 0 | 3:2 | 1 | 4 |
| 8 |
|
SV Rödinghausen | 2 | 1 | 0 | 1 | 5:2 | 3 | 3 |
| 9 |
|
Wuppertaler SV | 2 | 1 | 0 | 1 | 5:3 | 2 | 3 |
| 10 |
|
Fortuna Düsseldorf II | 2 | 1 | 0 | 1 | 3:3 | 0 | 3 |
| 11 |
|
SC Wiedenbrück | 2 | 1 | 0 | 1 | 2:2 | 0 | 3 |
| 12 |
|
Bor. Mönchengladbach II | 2 | 0 | 1 | 1 | 4:5 | -1 | 1 |
| 13 |
|
Alemannia Aachen | 2 | 0 | 1 | 1 | 3:4 | -1 | 1 |
| 14 |
|
Fortuna Köln | 2 | 0 | 1 | 1 | 1:2 | -1 | 1 |
| 15 |
|
SV 19 Straelen | 2 | 0 | 0 | 2 | 0:2 | -2 | 0 |
| 16 |
|
1. FC Bocholt | 2 | 0 | 0 | 2 | 2:5 | -3 | 0 |
| 17 |
|
SG Wattenscheid 09 | 2 | 0 | 0 | 2 | 2:8 | -6 | 0 |
| 18 |
|
1. FC Köln II | 2 | 0 | 0 | 2 | 1:8 | -7 | 0 |
| Promotie | |
| Degradatie | |
| Degradatie |
