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| 21.04.2023 | 19:30 | Fortuna Köln | - | SV 19 Straelen | 3:2 (0:1) | |
| 22.04.2023 | 14:00 | Bor. Mönchengladbach II | - | 1. FC Köln II | 2:2 (2:1) | |
| 14:00 | Preußen Münster | - | Fortuna Düsseldorf II | 2:0 (1:0) | ||
| 14:00 | Wuppertaler SV | - | 1. FC Düren | 3:1 (0:0) | ||
| 14:00 | SG Wattenscheid 09 | - | 1. FC Kaan-Marienborn | 2:5 (2:3) | ||
| 14:00 | 1. FC Bocholt | - | SV Rödinghausen | 1:1 (0:1) | ||
| 14:00 | SV Lippstadt 08 | - | Alemannia Aachen | 1:1 (0:0) | ||
| 23.04.2023 | 14:00 | Rot Weiss Ahlen | - | Rot-Weiß Oberhausen | 0:3 (0:1) | |
| 14:00 | SC Wiedenbrück | - | FC Schalke 04 II | 4:1 (1:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Preußen Münster | 31 | 24 | 4 | 3 | 82:32 | 50 | 76 |
| 2 |
|
Bor. Mönchengladbach II | 31 | 18 | 8 | 5 | 65:39 | 26 | 62 |
| 3 |
|
Wuppertaler SV | 31 | 16 | 9 | 6 | 66:40 | 26 | 57 |
| 4 |
|
SV Rödinghausen | 31 | 15 | 7 | 9 | 51:30 | 21 | 52 |
| 5 |
|
Fortuna Köln | 31 | 14 | 9 | 8 | 42:35 | 7 | 51 |
| 6 |
|
Alemannia Aachen | 31 | 14 | 8 | 9 | 43:37 | 6 | 50 |
| 7 |
|
1. FC Kaan-Marienborn | 31 | 14 | 6 | 11 | 50:48 | 2 | 48 |
| 8 |
|
Rot-Weiß Oberhausen | 31 | 13 | 8 | 10 | 53:44 | 9 | 47 |
| 9 |
|
FC Schalke 04 II | 31 | 12 | 9 | 10 | 57:44 | 13 | 45 |
| 10 |
|
SV Lippstadt 08 | 31 | 12 | 7 | 12 | 46:50 | -4 | 43 |
| 11 |
|
1. FC Düren | 31 | 11 | 6 | 14 | 38:53 | -15 | 39 |
| 12 |
|
SC Wiedenbrück | 31 | 10 | 7 | 14 | 41:40 | 1 | 37 |
| 13 |
|
Fortuna Düsseldorf II | 31 | 10 | 6 | 15 | 43:54 | -11 | 36 |
| 14 |
|
1. FC Köln II | 31 | 9 | 8 | 14 | 42:59 | -17 | 35 |
| 15 |
|
1. FC Bocholt | 31 | 8 | 9 | 14 | 42:60 | -18 | 33 |
| 16 |
|
Rot Weiss Ahlen | 31 | 8 | 5 | 18 | 49:67 | -18 | 29 |
| 17 |
|
SG Wattenscheid 09 | 31 | 6 | 3 | 22 | 40:89 | -49 | 21 |
| 18 |
|
SV 19 Straelen | 31 | 3 | 5 | 23 | 29:58 | -29 | 14 |
| Promotie | |
| Degradatie | |
| Degradatie |
