| 1. Ronde | 12.09.2021 | Fénix | - | Rentistas | 3:1 | ||||
| 2. Ronde | 18.09.2021 | Peñarol | - | Fénix | 0:0 | ||||
| 3. Ronde | 26.09.2021 | Fénix | - | Montevideo City Torque | 1:1 |  |
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| 4. Ronde | 02.10.2021 | Villa Española | - | Fénix | 1:2 | ||||
| 9. Ronde | 31.10.2021 | Fénix | - | Cerro Largo | 1:4 | |
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| 10. Ronde | 04.11.2021 | Progreso | - | Fénix | 1:0 | |
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| 11. Ronde | 08.11.2021 | Fénix | - | Sud América | 1:2 | |
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| 14. Ronde | 30.11.2021 | Fénix | - | Boston River | 0:0 | ||||
| 15. Ronde | 04.12.2021 | Montevideo Wanderers | - | Fénix | 1:1 |
Uruguay