| 4. Ronde | 06.08.2021 | CS Mioveni | - | CFR Cluj | 0:1 | ||||
| 5. Ronde | 13.08.2021 | CFR Cluj | - | Farul Constanța | 1:0 | ||||
| 7. Ronde | 29.08.2021 | CFR Cluj | - | FCSB | 4:1 | ||||
| 10. Ronde | 26.09.2021 | UTA Arad | - | CFR Cluj | 0:1 | ||||
| 11. Ronde | 03.10.2021 | CFR Cluj | - | Gaz Metan Mediaş | 2:1 | ||||
| 15. Ronde | 07.11.2021 | Dinamo Boekarest | - | CFR Cluj | 0:3 | ||||
| 17. Ronde | 29.11.2021 | CFR Cluj | - | Academica Clinceni | 2:0 |
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