| 5. Ronde | 30.12.2020 | AS Rejiche | - | JS Kairouan | 2:0 | ||||
| 7. Ronde | 10.01.2021 | US Monastir | - | JS Kairouan | 1:0 | ||||
| 8. Ronde | 13.01.2021 | JS Kairouan | - | AS Soliman | 2:3 |  |
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| 10. Ronde | 27.01.2021 | JS Kairouan | - | Étoile du Sahel | 1:3 | |
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| 11. Ronde | 30.01.2021 | CA Bizertin | - | JS Kairouan | 0:0 | ||||
| 12. Ronde | 03.02.2021 | JS Kairouan | - | CS Sfaxien | 0:4 | ||||
| 13. Ronde | 07.02.2021 | US Tataouine | - | JS Kairouan | 3:1 |  |
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| 14. Ronde | 27.02.2021 | Club Africain | - | JS Kairouan | 4:2 | ||||
| 15. Ronde | 03.03.2021 | JS Kairouan | - | Olympique Béja | 0:1 | ||||
| 16. Ronde | 07.03.2021 | Stade Tunisien | - | JS Kairouan | 2:0 | ||||
| 18. Ronde | 14.03.2021 | JS Kairouan | - | AS Rejiche | 0:1 |  |
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| 21. Ronde | 31.03.2021 | AS Soliman | - | JS Kairouan | 2:1 | ||||
| 22. Ronde | 03.04.2021 | JS Kairouan | - | US Ben Guerdane | 1:3 | ||||
| 23. Ronde | 07.04.2021 | Étoile du Sahel | - | JS Kairouan | 5:1 |
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