| 3. Ronde | 27.09.2021 | Egnatia Rrogozhine | - | KF Skënderbeu | 1:1 | ||||
| 4. Ronde | 02.10.2021 | Egnatia Rrogozhine | - | KS Kastrioti | 2:1 | ||||
| 5. Ronde | 16.10.2021 | KF Laçi | - | Egnatia Rrogozhine | 0:1 | ||||
| 8. Ronde | 08.11.2021 | Egnatia Rrogozhine | - | FK Vllaznia | 1:1 | ||||
| 9. Ronde | 22.11.2021 | Dinamo Tiranë | - | Egnatia Rrogozhine | 1:1 | ||||
| 13. Ronde | 12.12.2021 | KS Kastrioti | - | Egnatia Rrogozhine | 1:0 |  |
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| 14. Ronde | 19.12.2021 | Egnatia Rrogozhine | - | KF Laçi | 0:2 | ||||
| 15. Ronde | 23.12.2021 | KF Teuta Durrës | - | Egnatia Rrogozhine | 1:2 | |
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| 17. Ronde | 21.01.2022 | FK Vllaznia | - | Egnatia Rrogozhine | 1:1 | ||||
| 25. Ronde | 12.03.2022 | FK Partizani | - | Egnatia Rrogozhine | 2:2 | ||||
| 33. Ronde | 09.05.2022 | KF Teuta Durrës | - | Egnatia Rrogozhine | 3:1 | ||||
| 34. Ronde | 14.05.2022 | Egnatia Rrogozhine | - | FK Partizani | 0:1 | ||||
| 36. Ronde | 26.05.2022 | Egnatia Rrogozhine | - | Dinamo Tiranë | 1:1 |
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