| 2. Ronde | 26.09.2021 | AC Libertas | - | SC Faetano | 4:2 | ||||
| 4. Ronde | 16.10.2021 | SS Cosmos | - | SC Faetano | 0:3 | ||||
| 6. Ronde | 24.10.2021 | SS Folgore/Falciano | - | SC Faetano | 0:0 | ||||
| 18. Ronde | 29.01.2022 | SS Virtus | - | SC Faetano | 0:0 | ||||
| 22. Ronde | 20.02.2022 | FC Domagnano | - | SC Faetano | 1:3 | ||||
| 14. Ronde | 23.02.2022 | SC Faetano | - | SP Tre Penne | 0:0 |  |
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| 24. Ronde | 05.03.2022 | AC Juvenes/Dogana | - | SC Faetano | 1:2 | |
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| 26. Ronde | 13.03.2022 | SC Faetano | - | SP Tre Fiori | 0:1 | ||||
| 15. Ronde | 16.03.2022 | SP Cailungo | - | SC Faetano | 0:4 | ||||
| 17. Ronde | 05.04.2022 | SC Faetano | - | AC Libertas | 1:2 | ||||
| 28. Ronde | 09.04.2022 | SC Faetano | - | SS Murata | 3:2 | |
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| 30. Ronde | 21.04.2022 | SC Faetano | - | SP Cailungo | 4:1 |
San Marino