| 5. Ronde | 17.04.2021 | ŠKF Sereď | - | MFK Zemplín Michalovce | 2:0 | ||||
| 6. Ronde | 24.04.2021 | FK Senica | - | MFK Zemplín Michalovce | 1:1 |  |
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| 7. Ronde | 01.05.2021 | MFK Zemplín Michalovce | - | MFK Ružomberok | 2:1 | |
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| 9. Ronde | 15.05.2021 | MFK Zemplín Michalovce | - | ŠKF Sereď | 2:2 | ||||
| 10. Ronde | 22.05.2021 | FC Nitra | - | MFK Zemplín Michalovce | 0:4 |
Spanje