| 1. Ronde | 18.01.2021 | Plaza Colonia | - | Liverpool | 0:0 | ||||
| 2. Ronde | 21.01.2021 | Plaza Colonia | - | Progreso | 0:1 | ||||
| 3. Ronde | 29.01.2021 | Fénix | - | Plaza Colonia | 3:3 | ||||
| 4. Ronde | 04.02.2021 | Plaza Colonia | - | CA Cerro | 2:1 | ||||
| 5. Ronde | 07.02.2021 | Defensor Sporting | - | Plaza Colonia | 3:2 |  |
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| 6. Ronde | 10.02.2021 | Plaza Colonia | - | Danubio | 3:0 | ||||
| 7. Ronde | 14.02.2021 | Nacional | - | Plaza Colonia | 1:1 | |
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| 9. Ronde | 22.02.2021 | Deportivo Maldonado | - | Plaza Colonia | 1:1 | ||||
| 11. Ronde | 07.03.2021 | Cerro Largo | - | Plaza Colonia | 3:1 | ||||
| 13. Ronde | 20.03.2021 | Peñarol | - | Plaza Colonia | 1:3 | ||||
| 15. Ronde | 29.03.2021 | Montevideo City Torque | - | Plaza Colonia | 2:0 |
Uruguay