| 2. Ronde | 13.02.2022 | Liverpool | - | Albion | 4:0 | ||||
| 3. Ronde | 20.02.2022 | Albion | - | Peñarol | 1:1 | ||||
| 4. Ronde | 28.02.2022 | Montevideo City Torque | - | Albion | 1:2 | ||||
| 7. Ronde | 02.04.2022 | Albion | - | Boston River | 1:2 | ||||
| 8. Ronde | 10.04.2022 | River Plate | - | Albion | 4:1 | ||||
| 9. Ronde | 16.04.2022 | Albion | - | Cerro Largo | 2:1 | ||||
| 12. Ronde | 15.05.2022 | Albion | - | Cerrito | 2:2 |  |
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| 13. Ronde | 21.05.2022 | Nacional | - | Albion | 2:0 |
Uruguay