| 1. Ronde | 07.03.2022 | Paphos FC | - | Apollon Limassol | 0:0 | ||||
| 2. Ronde | 13.03.2022 | Apollon Limassol | - | Anorthosis Famagusta | 1:1 |  |
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| 3. Ronde | 20.03.2022 | APOEL Nicosia | - | Apollon Limassol | 0:0 | ||||
| 4. Ronde | 03.04.2022 | Apollon Limassol | - | Aris Limassol | 1:1 | ||||
| 5. Ronde | 09.04.2022 | AEK Larnaca | - | Apollon Limassol | 3:3 | |
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| 6. Ronde | 16.04.2022 | Apollon Limassol | - | Paphos FC | 0:2 | ||||
| 7. Ronde | 30.04.2022 | Anorthosis Famagusta | - | Apollon Limassol | 1:1 | |
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| 8. Ronde | 08.05.2022 | Apollon Limassol | - | APOEL Nicosia | 3:2 | ||||
| 9. Ronde | 15.05.2022 | Aris Limassol | - | Apollon Limassol | 1:4 | ||||
| 10. Ronde | 22.05.2022 | Apollon Limassol | - | AEK Larnaca | 0:1 |
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