| 3. Ronde | 23.01.2022 | LD Alajuelense | - | AD Guanacasteca | 4:0 |  |
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| 4. Ronde | 04.02.2022 | Municipal Pérez Zeledón | - | LD Alajuelense | 2:1 | ||||
| 5. Ronde | 10.02.2022 | LD Alajuelense | - | CS Cartaginés | 3:2 | ||||
| 6. Ronde | 13.02.2022 | LD Alajuelense | - | Deportivo Saprissa | 0:1 | |
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| 1. Ronde | 17.02.2022 | Sporting FC | - | LD Alajuelense | 2:1 | ||||
| 7. Ronde | 20.02.2022 | Jicaral | - | LD Alajuelense | 0:3 | ||||
| 8. Ronde | 27.02.2022 | LD Alajuelense | - | Municipal Grecia | 1:0 | |
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| 9. Ronde | 03.03.2022 | CS Herediano | - | LD Alajuelense | 1:1 | ||||
| 10. Ronde | 07.03.2022 | AD San Carlos | - | LD Alajuelense | 0:3 Toeg. | ||||
| 11. Ronde | 02.04.2022 | LD Alajuelense | - | Santos de Guápiles | 0:2 | ||||
| 14. Ronde | 16.04.2022 | AD Guanacasteca | - | LD Alajuelense | 0:3 | ||||
| 15. Ronde | 20.04.2022 | LD Alajuelense | - | Municipal Pérez Zeledón | 3:1 | ||||
| 16. Ronde | 24.04.2022 | CS Cartaginés | - | LD Alajuelense | 1:2 | ||||
| 18. Ronde | 01.05.2022 | LD Alajuelense | - | Jicaral | 3:0 | ||||
| 19. Ronde | 04.05.2022 | Municipal Grecia | - | LD Alajuelense | 1:1 | ||||
| 20. Ronde | 09.05.2022 | LD Alajuelense | - | CS Herediano | 2:1 | ||||
| 22. Ronde | 16.05.2022 | Santos de Guápiles | - | LD Alajuelense | 2:0 |
Costa Rica