| 10. Ronde | 06.03.2021 | Tigres FC | - | Real Cartagena | 0:0 | ||||
| 11. Ronde | 14.03.2021 | Real Santander | - | Real Cartagena | 0:3 | ||||
| 12. Ronde | 22.03.2021 | Real Cartagena | - | Bogotá FC | 1:1 | ||||
| 13. Ronde | 28.03.2021 | Fortaleza FC | - | Real Cartagena | 1:1 |  |
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| 14. Ronde | 03.04.2021 | Real Cartagena | - | Leones FC | 2:1 | ||||
| 15. Ronde | 09.04.2021 | Atlético Huila | - | Real Cartagena | 4:1 |
Colombia