| 1. Ronde | 05.02.2022 | Tauro FC | - | Sporting San Miguelito | 3:3 | ||||
| 6. Ronde | 08.03.2022 | UD Universitario | - | Sporting San Miguelito | 0:2 | ||||
| 8. Ronde | 20.03.2022 | Veraguas United | - | Sporting San Miguelito | 1:2 | ||||
| 13. Ronde | 23.04.2022 | Plaza Amador | - | Sporting San Miguelito | 1:1 | ||||
| 15. Ronde | 30.04.2022 | Sporting San Miguelito | - | Alianza | 1:0 |
Panama