| 1. Ronde | 08.08.2021 | Stade Rennais | - | RC Lens | 1:1 | ||||
| 2. Ronde | 15.08.2021 | RC Lens | - | AS Saint-Étienne | 2:2 | ||||
| 7. Ronde | 22.09.2021 | RC Lens | - | RC Strasbourg | 0:1 | ||||
| 8. Ronde | 26.09.2021 | Olympique Marseille | - | RC Lens | 2:3 | ||||
| 10. Ronde | 17.10.2021 | Montpellier HSC | - | RC Lens | 1:0 |  |
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| 15. Ronde | 26.11.2021 | RC Lens | - | Angers SCO | 2:2 | ||||
| 19. Ronde | 22.12.2021 | OGC Nice | - | RC Lens | 2:1 | ||||
| 23. Ronde | 06.02.2022 | FC Lorient | - | RC Lens | 2:0 | |
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| 24. Ronde | 13.02.2022 | RC Lens | - | Girondins Bordeaux | 3:2 | ||||
| 25. Ronde | 19.02.2022 | RC Lens | - | Olympique Lyonnais | 1:1 | ||||
| 30. Ronde | 03.04.2022 | RC Strasbourg | - | RC Lens | 1:0 | ||||
| 33. Ronde | 20.04.2022 | RC Lens | - | Montpellier HSC | 2:0 | ||||
| 34. Ronde | 23.04.2022 | Paris Saint-Germain | - | RC Lens | 1:1 | ||||
| 35. Ronde | 30.04.2022 | RC Lens | - | FC Nantes | 2:2 |
Frankrijk