| 2. Ronde | 02.04.2021 | Treaty United | - | Wexford FC | 1:0 |  |
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| 4. Ronde | 16.04.2021 | Galway United | - | Treaty United | 1:1 | ||||
| 5. Ronde | 23.04.2021 | Treaty United | - | Cork City | 2:1 |  |
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| 6. Ronde | 30.04.2021 | Shelbourne FC | - | Treaty United | 2:2 |  |
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| 7. Ronde | 07.05.2021 | UC Dublin | - | Treaty United | 3:2 | ||||
| 8. Ronde | 14.05.2021 | Treaty United | - | Athlone Town | 1:0 | ||||
| 9. Ronde | 21.05.2021 | Cabinteely FC | - | Treaty United | 2:1 | |
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| 12. Ronde | 19.06.2021 | Cobh Ramblers | - | Treaty United | 0:2 | |
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| 13. Ronde | 25.06.2021 | Treaty United | - | Galway United | 0:1 | |
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| 14. Ronde | 02.07.2021 | Cork City | - | Treaty United | 2:3 | ||||
| 16. Ronde | 16.07.2021 | Treaty United | - | UC Dublin | 2:1 | ||||
| 17. Ronde | 30.07.2021 | Athlone Town | - | Treaty United | 1:4 | ||||
| 18. Ronde | 06.08.2021 | Treaty United | - | Cabinteely FC | 1:4 | |
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| 21. Ronde | 03.09.2021 | Treaty United | - | Cobh Ramblers | 3:0 | ||||
| 22. Ronde | 10.09.2021 | Galway United | - | Treaty United | 0:0 | ||||
| 23. Ronde | 24.09.2021 | Treaty United | - | Cork City | 0:0 | ||||
| 24. Ronde | 01.10.2021 | Shelbourne FC | - | Treaty United | 1:0 | ||||
| 27. Ronde | 29.10.2021 | Cabinteely FC | - | Treaty United | 0:2 |
Ierland