| 2. Ronde | 08.08.2021 | Municipal Limeño | - | Luis Ángel Firpo | 1:1 | ||||
| 3. Ronde | 11.08.2021 | Luis Ángel Firpo | - | Platense Zacatecoluca | 3:2 | ||||
| 4. Ronde | 15.08.2021 | Alianza | - | Luis Ángel Firpo | 2:2 | ||||
| 5. Ronde | 22.08.2021 | AD Chalatenango | - | Luis Ángel Firpo | 0:2 | ||||
| 6. Ronde | 25.08.2021 | Luis Ángel Firpo | - | Once Municipal | 2:2 | ||||
| 7. Ronde | 29.08.2021 | FAS | - | Luis Ángel Firpo | 3:1 | ||||
| 15. Ronde | 24.10.2021 | Luis Ángel Firpo | - | Alianza | 2:1 | ||||
| 16. Ronde | 31.10.2021 | Luis Ángel Firpo | - | AD Chalatenango | 4:2 | ||||
| 17. Ronde | 02.11.2021 | Once Municipal | - | Luis Ángel Firpo | 1:0 | ||||
| 18. Ronde | 07.11.2021 | Luis Ángel Firpo | - | FAS | 2:0 | ||||
| 19. Ronde | 14.11.2021 | Isidro Metapán | - | Luis Ángel Firpo | 2:1 |  |
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| 20. Ronde | 18.11.2021 | Luis Ángel Firpo | - | Atlético Marte | 2:0 | ||||
| 21. Ronde | 21.11.2021 | Santa Tecla FC | - | Luis Ángel Firpo | 2:2 | |
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| 22. Ronde | 27.11.2021 | Luis Ángel Firpo | - | CD Águila | 1:0 |
El Salvador