| 1. Ronde | 16.01.2021 | Orsomarso SC | - | Barranquilla FC | 2:2 | ||||
| 2. Ronde | 23.01.2021 | Valledupar FC | - | Orsomarso SC | 3:4 |  |
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| 3. Ronde | 30.01.2021 | Orsomarso SC | - | Llaneros FC | 0:0 | ||||
| 4. Ronde | 06.02.2021 | Unión Magdalena | - | Orsomarso SC | 1:1 | ||||
| 6. Ronde | 15.02.2021 | Tigres FC | - | Orsomarso SC | 2:0 | ||||
| 7. Ronde | 20.02.2021 | Boca Juniors de Cali | - | Orsomarso SC | 0:0 |  |
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| 8. Ronde | 27.02.2021 | Orsomarso SC | - | Real Cartagena | 3:3 | ||||
| 9. Ronde | 04.03.2021 | Real Santander | - | Orsomarso SC | 1:2 | ||||
| 10. Ronde | 07.03.2021 | Orsomarso SC | - | Bogotá FC | 4:2 | |
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| 11. Ronde | 14.03.2021 | Fortaleza FC | - | Orsomarso SC | 3:1 | |
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| 14. Ronde | 03.04.2021 | Orsomarso SC | - | Cortuluá | 1:2 |
Colombia