| 2. Ronde | 02.08.2021 | Orsomarso SC | - | Llaneros FC | 0:2 |  |
|||
| 3. Ronde | 07.08.2021 | Tigres FC | - | Orsomarso SC | 1:2 | ||||
| 5. Ronde | 21.08.2021 | Bogotá FC | - | Orsomarso SC | 3:0 | ||||
| 6. Ronde | 28.08.2021 | Orsomarso SC | - | Atlético FC | 1:2 | ||||
| 9. Ronde | 21.09.2021 | Orsomarso SC | - | Boyacá Chicó | 2:1 | ||||
| 11. Ronde | 02.10.2021 | Orsomarso SC | - | Real Santander | 3:1 | ||||
| 12. Ronde | 11.10.2021 | Cortuluá | - | Orsomarso SC | 1:1 | ||||
| 13. Ronde | 18.10.2021 | Orsomarso SC | - | Unión Magdalena | 1:2 |  |
|||
| 14. Ronde | 23.10.2021 | Boca Juniors de Cali | - | Orsomarso SC | 2:1 | |
|||
| 15. Ronde | 30.10.2021 | Orsomarso SC | - | Real Cartagena | 1:1 |
Colombia