| 2. Ronde | 30.07.2010 | Oţelul Galaţi | - | Pandurii Târgu Jiu | 2:0 | ||||
| 3. Ronde | 08.08.2010 | Pandurii Târgu Jiu | - | Dinamo Boekarest | 2:2 |  |
 |
||
| 4. Ronde | 13.08.2010 | Gloria Bistrița (old) | - | Pandurii Târgu Jiu | 3:0 | ||||
| 5. Ronde | 21.08.2010 | Pandurii Târgu Jiu | - | Gaz Metan Mediaş | 0:0 | ||||
| 6. Ronde | 28.08.2010 | CFR Cluj | - | Pandurii Târgu Jiu | 2:1 | ||||
| 7. Ronde | 13.09.2010 | Pandurii Târgu Jiu | - | FC Universitatea Craiova | 3:1 | |
|||
| 8. Ronde | 17.09.2010 | FC Victoria Brăneşti | - | Pandurii Târgu Jiu | 2:0 | ||||
| 9. Ronde | 26.09.2010 | Pandurii Târgu Jiu | - | FC Timişoara | 0:1 | ||||
| 10. Ronde | 01.10.2010 | Astra Ploieşti | - | Pandurii Târgu Jiu | 2:0 | ||||
| 11. Ronde | 16.10.2010 | Pandurii Târgu Jiu | - | Sportul Studenţesc | 1:0 | ||||
| 13. Ronde | 01.11.2010 | Rapid Bucureşti | - | Pandurii Târgu Jiu | 1:1 | ||||
| 14. Ronde | 06.11.2010 | Pandurii Târgu Jiu | - | FCM Târgu Mureş | 4:1 | ||||
| 15. Ronde | 13.11.2010 | Universitatea Cluj | - | Pandurii Târgu Jiu | 1:1 | ||||
| 16. Ronde | 19.11.2010 | Pandurii Târgu Jiu | - | FC Brașov | 2:1 | ||||
| 17. Ronde | 26.11.2010 | FC Vaslui | - | Pandurii Târgu Jiu | 3:1 |
Roemenië